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Page 1
CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates.
Watkins BK, Tkachev V, Furlan SN, Hunt DJ, Betz K, Yu A, Brown M, Poirier N, Zheng HB, Taraseviciute A, Colonna L, Mary C, Blancho G, Soulillou JP, Panoskaltsis-Mortari A, Sharma P, Garcia A, Strobert E, Hamby K, Garrett A, Deane T, Blazar BR, Vanhove B, Kean LS. Watkins BK, et al. Among authors: strobert e. J Clin Invest. 2018 Aug 31;128(9):3991-4007. doi: 10.1172/JCI98793. Epub 2018 Aug 13. J Clin Invest. 2018. PMID: 30102255 Free PMC article.
GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression.
Miller WP, Srinivasan S, Panoskaltsis-Mortari A, Singh K, Sen S, Hamby K, Deane T, Stempora L, Beus J, Turner A, Wheeler C, Anderson DC, Sharma P, Garcia A, Strobert E, Elder E, Crocker I, Crenshaw T, Penedo MC, Ward T, Song M, Horan J, Larsen CP, Blazar BR, Kean LS. Miller WP, et al. Among authors: strobert e. Blood. 2010 Dec 9;116(24):5403-18. doi: 10.1182/blood-2010-06-289272. Epub 2010 Sep 10. Blood. 2010. PMID: 20833977 Free PMC article.
CD40 blockade combines with CTLA4Ig and sirolimus to produce mixed chimerism in an MHC-defined rhesus macaque transplant model.
Page A, Srinivasan S, Singh K, Russell M, Hamby K, Deane T, Sen S, Stempora L, Leopardi F, Price AA, Strobert E, Reimann KA, Kirk AD, Larsen CP, Kean LS. Page A, et al. Among authors: strobert e. Am J Transplant. 2012 Jan;12(1):115-25. doi: 10.1111/j.1600-6143.2011.03737.x. Epub 2011 Sep 19. Am J Transplant. 2012. PMID: 21929643 Free PMC article.
Induction of chimerism in rhesus macaques through stem cell transplant and costimulation blockade-based immunosuppression.
Kean LS, Adams AB, Strobert E, Hendrix R, Gangappa S, Jones TR, Shirasugi N, Rigby MR, Hamby K, Jiang J, Bello H, Anderson D, Cardona K, Durham MM, Pearson TC, Larsen CP. Kean LS, et al. Among authors: strobert e. Am J Transplant. 2007 Feb;7(2):320-35. doi: 10.1111/j.1600-6143.2006.01622.x. Am J Transplant. 2007. PMID: 17241112 Free article.
Evidence for kidney rejection after combined bone marrow and renal transplantation despite ongoing whole-blood chimerism in rhesus macaques.
Ramakrishnan SK, Page A, Farris AB 3rd, Singh K, Leopardi F, Hamby K, Sen S, Polnett A, Deane T, Song M, Stempora L, Strobert E, Kirk AD, Larsen CP, Kean LS. Ramakrishnan SK, et al. Among authors: strobert e. Am J Transplant. 2012 Jul;12(7):1755-64. doi: 10.1111/j.1600-6143.2012.04045.x. Epub 2012 May 29. Am J Transplant. 2012. PMID: 22642491 Free PMC article.
CD8-predominant T-cell CNS infiltration accompanies GVHD in primates and is improved with immunoprophylaxis.
Kaliyaperumal S, Watkins B, Sharma P, Furlan S, Ramakrishnan S, Giver C, Garcia A, Courtney C, Knight H, Strobert E, Elder E, Crenshaw T, Blazar BR, Waller EK, Westmoreland S, Kean LS. Kaliyaperumal S, et al. Among authors: strobert e. Blood. 2014 Mar 20;123(12):1967-9. doi: 10.1182/blood-2014-01-547612. Blood. 2014. PMID: 24652969 Free PMC article. No abstract available.
An MHC-defined primate model reveals significant rejection of bone marrow after mixed chimerism induction despite full MHC matching.
Larsen CP, Page A, Linzie KH, Russell M, Deane T, Stempora L, Strobert E, Penedo MC, Ward T, Wiseman R, O'Connor D, Miller W, Sen S, Singh K, Kean LS. Larsen CP, et al. Among authors: strobert e. Am J Transplant. 2010 Nov;10(11):2396-409. doi: 10.1111/j.1600-6143.2010.03272.x. Epub 2010 Sep 17. Am J Transplant. 2010. PMID: 20849552 Free PMC article.
LFA-1-specific therapy prolongs allograft survival in rhesus macaques.
Badell IR, Russell MC, Thompson PW, Turner AP, Weaver TA, Robertson JM, Avila JG, Cano JA, Johnson BE, Song M, Leopardi FV, Swygert S, Strobert EA, Ford ML, Kirk AD, Larsen CP. Badell IR, et al. Among authors: strobert ea. J Clin Invest. 2010 Dec;120(12):4520-31. doi: 10.1172/JCI43895. Epub 2010 Nov 22. J Clin Invest. 2010. PMID: 21099108 Free PMC article.
75 results