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508 results

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Page 1
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Kayagaki N, Stowe IB, Lee BL, O'Rourke K, Anderson K, Warming S, Cuellar T, Haley B, Roose-Girma M, Phung QT, Liu PS, Lill JR, Li H, Wu J, Kummerfeld S, Zhang J, Lee WP, Snipas SJ, Salvesen GS, Morris LX, Fitzgerald L, Zhang Y, Bertram EM, Goodnow CC, Dixit VM. Kayagaki N, et al. Among authors: lee wp, lee bl. Nature. 2015 Oct 29;526(7575):666-71. doi: 10.1038/nature15541. Epub 2015 Sep 16. Nature. 2015. PMID: 26375259
The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation.
Ratner D, Orning MP, Proulx MK, Wang D, Gavrilin MA, Wewers MD, Alnemri ES, Johnson PF, Lee B, Mecsas J, Kayagaki N, Goguen JD, Lien E. Ratner D, et al. PLoS Pathog. 2016 Dec 2;12(12):e1006035. doi: 10.1371/journal.ppat.1006035. eCollection 2016 Dec. PLoS Pathog. 2016. PMID: 27911947 Free PMC article.
IRF2 transcriptionally induces GSDMD expression for pyroptosis.
Kayagaki N, Lee BL, Stowe IB, Kornfeld OS, O'Rourke K, Mirrashidi KM, Haley B, Watanabe C, Roose-Girma M, Modrusan Z, Kummerfeld S, Reja R, Zhang Y, Cho V, Andrews TD, Morris LX, Goodnow CC, Bertram EM, Dixit VM. Kayagaki N, et al. Among authors: lee bl. Sci Signal. 2019 May 21;12(582):eaax4917. doi: 10.1126/scisignal.aax4917. Sci Signal. 2019. PMID: 31113851
MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.
Vande Walle L, Stowe IB, Šácha P, Lee BL, Demon D, Fossoul A, Van Hauwermeiren F, Saavedra PHV, Šimon P, Šubrt V, Kostka L, Stivala CE, Pham VC, Staben ST, Yamazoe S, Konvalinka J, Kayagaki N, Lamkanfi M. Vande Walle L, et al. Among authors: lee bl. PLoS Biol. 2019 Sep 16;17(9):e3000354. doi: 10.1371/journal.pbio.3000354. eCollection 2019 Sep. PLoS Biol. 2019. PMID: 31525186 Free PMC article.
Correction: MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.
Walle LV, Stowe IB, Šácha P, Lee BL, Demon D, Fossoul A, Van Hauwermeiren F, Saavedra PHV, Šimon P, Šubr V, Kostka L, Stivala CE, Pham VC, Staben ST, Yamazoe S, Konvalinka J, Kayagaki N, Lamkanfi M. Walle LV, et al. Among authors: lee bl. PLoS Biol. 2019 Oct 16;17(10):e3000529. doi: 10.1371/journal.pbio.3000529. eCollection 2019 Oct. PLoS Biol. 2019. PMID: 31618263 Free PMC article.
508 results