Staals RHJ - Search Results

1

Bioinformatic evidence of widespread priming in type I and II CRISPR-Cas systems.

Nicholson TJ, Jackson SA, Croft BI, Staals RHJ, Fineran PC, Brown CM. Nicholson TJ, et al. Among authors: staals rhj. RNA Biol. 2019 Apr;16(4):566-576. doi: 10.1080/15476286.2018.1509662. Epub 2018 Sep 18. RNA Biol. 2019. PMID: 30157725 Free PMC article.

2

CRISPR-Cas systems preferentially target the leading regions of MOBF conjugative plasmids.

Westra ER, Staals RH, Gort G, Høgh S, Neumann S, de la Cruz F, Fineran PC, Brouns SJ. Westra ER, et al. RNA Biol. 2013 May;10(5):749-61. doi: 10.4161/rna.24202. Epub 2013 Mar 27. RNA Biol. 2013. PMID: 23535265 Free PMC article.

3

Degenerate target sites mediate rapid primed CRISPR adaptation.

Fineran PC, Gerritzen MJ, Suárez-Diez M, Künne T, Boekhorst J, van Hijum SA, Staals RH, Brouns SJ. Fineran PC, et al. Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):E1629-38. doi: 10.1073/pnas.1400071111. Epub 2014 Apr 7. Proc Natl Acad Sci U S A. 2014. PMID: 24711427 Free PMC article.

4

Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer.

Richter C, Dy RL, McKenzie RE, Watson BN, Taylor C, Chang JT, McNeil MB, Staals RH, Fineran PC. Richter C, et al. Nucleic Acids Res. 2014 Jul;42(13):8516-26. doi: 10.1093/nar/gku527. Epub 2014 Jul 2. Nucleic Acids Res. 2014. PMID: 24990370 Free PMC article.

5

The Cpf1 CRISPR-Cas protein expands genome-editing tools.

Fagerlund RD, Staals RH, Fineran PC. Fagerlund RD, et al. Genome Biol. 2015 Nov 17;16:251. doi: 10.1186/s13059-015-0824-9. Genome Biol. 2015. PMID: 26578176 Free PMC article.

6

Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system.

Wilkinson ME, Nakatani Y, Staals RH, Kieper SN, Opel-Reading HK, McKenzie RE, Fineran PC, Krause KL. Wilkinson ME, et al. Biochem J. 2016 Apr 15;473(8):1063-72. doi: 10.1042/BCJ20160078. Epub 2016 Feb 29. Biochem J. 2016. PMID: 26929403

7

CRISPRDetect: A flexible algorithm to define CRISPR arrays.

Biswas A, Staals RH, Morales SE, Fineran PC, Brown CM. Biswas A, et al. BMC Genomics. 2016 May 17;17:356. doi: 10.1186/s12864-016-2627-0. BMC Genomics. 2016. PMID: 27184979 Free PMC article.

8

Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species.

Pawluk A, Staals RH, Taylor C, Watson BN, Saha S, Fineran PC, Maxwell KL, Davidson AR. Pawluk A, et al. Nat Microbiol. 2016 Jun 13;1(8):16085. doi: 10.1038/nmicrobiol.2016.85. Nat Microbiol. 2016. PMID: 27573108

9

Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR-Cas system.

Staals RH, Jackson SA, Biswas A, Brouns SJ, Brown CM, Fineran PC. Staals RH, et al. Nat Commun. 2016 Oct 3;7:12853. doi: 10.1038/ncomms12853. Nat Commun. 2016. PMID: 27694798 Free PMC article.

10

Quorum Sensing Controls Adaptive Immunity through the Regulation of Multiple CRISPR-Cas Systems.

Patterson AG, Jackson SA, Taylor C, Evans GB, Salmond GPC, Przybilski R, Staals RHJ, Fineran PC. Patterson AG, et al. Among authors: staals rhj. Mol Cell. 2016 Dec 15;64(6):1102-1108. doi: 10.1016/j.molcel.2016.11.012. Epub 2016 Nov 17. Mol Cell. 2016. PMID: 27867010 Free PMC article.

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