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SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.
Buchanan SG, Hendle J, Lee PS, Smith CR, Bounaud PY, Jessen KA, Tang CM, Huser NH, Felce JD, Froning KJ, Peterman MC, Aubol BE, Gessert SF, Sauder JM, Schwinn KD, Russell M, Rooney IA, Adams J, Leon BC, Do TH, Blaney JM, Sprengeler PA, Thompson DA, Smyth L, Pelletier LA, Atwell S, Holme K, Wasserman SR, Emtage S, Burley SK, Reich SH. Buchanan SG, et al. Among authors: leon bc. Mol Cancer Ther. 2009 Dec;8(12):3181-90. doi: 10.1158/1535-7163.MCT-09-0477. Mol Cancer Ther. 2009. PMID: 19934279
A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase.
Atwell S, Adams JM, Badger J, Buchanan MD, Feil IK, Froning KJ, Gao X, Hendle J, Keegan K, Leon BC, Müller-Dieckmann HJ, Nienaber VL, Noland BW, Post K, Rajashankar KR, Ramos A, Russell M, Burley SK, Buchanan SG. Atwell S, et al. Among authors: leon bc. J Biol Chem. 2004 Dec 31;279(53):55827-32. doi: 10.1074/jbc.M409792200. Epub 2004 Oct 26. J Biol Chem. 2004. PMID: 15507431 Free article.
[Eimeria and eimeriasis in human pathology].
LEON LA, DE LEON BC. LEON LA, et al. Among authors: de leon bc. Medicina (Mex). 1959 Jul 10;39:283-90. Medicina (Mex). 1959. PMID: 14415772 Spanish. No abstract available.