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Page 1
The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel.
Monks A, Zhao Y, Hose C, Hamed H, Krushkal J, Fang J, Sonkin D, Palmisano A, Polley EC, Fogli LK, Konaté MM, Miller SB, Simpson MA, Voth AR, Li MC, Harris E, Wu X, Connelly JW, Rapisarda A, Teicher BA, Simon R, Doroshow JH. Monks A, et al. Among authors: konate mm. Cancer Res. 2018 Dec 15;78(24):6807-6817. doi: 10.1158/0008-5472.CAN-18-0989. Epub 2018 Oct 24. Cancer Res. 2018. PMID: 30355619 Free PMC article.
Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases.
Lu J, Risbood P, Kane CT Jr, Hossain MT, Anderson L, Hill K, Monks A, Wu Y, Antony S, Juhasz A, Liu H, Jiang G, Harris E, Roy K, Meitzler JL, Konaté M, Doroshow JH. Lu J, et al. Biochem Pharmacol. 2017 Nov 1;143:25-38. doi: 10.1016/j.bcp.2017.07.007. Epub 2017 Jul 11. Biochem Pharmacol. 2017. PMID: 28709950 Free PMC article.
NADPH oxidase 5 (NOX5)-induced reactive oxygen signaling modulates normoxic HIF-1α and p27Kip1 expression in malignant melanoma and other human tumors.
Antony S, Jiang G, Wu Y, Meitzler JL, Makhlouf HR, Haines DC, Butcher D, Hoon DS, Ji J, Zhang Y, Juhasz A, Lu J, Liu H, Dahan I, Konate M, Roy KK, Doroshow JH. Antony S, et al. Mol Carcinog. 2017 Dec;56(12):2643-2662. doi: 10.1002/mc.22708. Epub 2017 Aug 30. Mol Carcinog. 2017. PMID: 28762556 Free PMC article.
IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells.
Wu Y, Konaté MM, Lu J, Makhlouf H, Chuaqui R, Antony S, Meitzler JL, Difilippantonio MJ, Liu H, Juhasz A, Jiang G, Dahan I, Roy K, Doroshow JH. Wu Y, et al. Among authors: konate mm. J Immunol. 2019 Nov 1;203(9):2532-2544. doi: 10.4049/jimmunol.1800469. Epub 2019 Sep 23. J Immunol. 2019. PMID: 31548328 Free PMC article.
Clinical Evolution of Epithelial-Mesenchymal Transition in Human Carcinomas.
Navas T, Kinders RJ, Lawrence SM, Ferry-Galow KV, Borgel S, Hollingshead MG, Srivastava AK, Alcoser SY, Makhlouf HR, Chuaqui R, Wilsker DF, Konaté MM, Miller SB, Voth AR, Chen L, Vilimas T, Subramanian J, Rubinstein L, Kummar S, Chen AP, Bottaro DP, Doroshow JH, Parchment RE. Navas T, et al. Among authors: konate mm. Cancer Res. 2020 Jan 15;80(2):304-318. doi: 10.1158/0008-5472.CAN-18-3539. Epub 2019 Nov 15. Cancer Res. 2020. PMID: 31732654 Free PMC article.
Inhibiting the Activity of NADPH Oxidase in Cancer.
Konaté MM, Antony S, Doroshow JH. Konaté MM, et al. Antioxid Redox Signal. 2020 Aug 20;33(6):435-454. doi: 10.1089/ars.2020.8046. Epub 2020 Apr 17. Antioxid Redox Signal. 2020. PMID: 32008376 Free PMC article.
NADPH oxidase 1 is highly expressed in human large and small bowel cancers.
Lu J, Jiang G, Wu Y, Antony S, Meitzler JL, Juhasz A, Liu H, Roy K, Makhlouf H, Chuaqui R, Butcher D, Konaté MM, Doroshow JH. Lu J, et al. Among authors: konate mm. PLoS One. 2020 May 19;15(5):e0233208. doi: 10.1371/journal.pone.0233208. eCollection 2020. PLoS One. 2020. PMID: 32428030 Free PMC article.
Molecular Profiling-Based Assignment of Cancer Therapy (NCI-MPACT): A Randomized Multicenter Phase II Trial.
Chen AP, Kummar S, Moore N, Rubinstein LV, Zhao Y, Williams PM, Palmisano A, Sims D, O'Sullivan Coyne G, Rosenberger CL, Simpson M, Raghav KPS, Meric-Bernstam F, Leong S, Waqar S, Foster JC, Konaté MM, Das B, Karlovich C, Lih CJ, Polley E, Simon R, Li MC, Piekarz R, Doroshow JH. Chen AP, et al. Among authors: konate mm. JCO Precis Oncol. 2021 Jan 12;5:PO.20.00372. doi: 10.1200/PO.20.00372. eCollection 2021. JCO Precis Oncol. 2021. PMID: 33928209 Free PMC article. Clinical Trial.
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