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Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling.
Lund H, Pieber M, Parsa R, Grommisch D, Ewing E, Kular L, Han J, Zhu K, Nijssen J, Hedlund E, Needhamsen M, Ruhrmann S, Guerreiro-Cacais AO, Berglund R, Forteza MJ, Ketelhuth DFJ, Butovsky O, Jagodic M, Zhang XM, Harris RA. Lund H, et al. Among authors: parsa r. Nat Immunol. 2018 May;19(5):1-7. doi: 10.1038/s41590-018-0091-5. Epub 2018 Apr 16. Nat Immunol. 2018. PMID: 29662171 Free PMC article.
TGFβ regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte-derived dendritic cells.
Parsa R, Lund H, Tosevski I, Zhang XM, Malipiero U, Beckervordersandforth J, Merkler D, Prinz M, Gyllenberg A, James T, Warnecke A, Hillert J, Alfredsson L, Kockum I, Olsson T, Fontana A, Suter T, Harris RA. Parsa R, et al. Glia. 2016 Nov;64(11):1925-37. doi: 10.1002/glia.23033. Epub 2016 Aug 1. Glia. 2016. PMID: 27479807 Free PMC article.
48 results