Supek F - Search Results

1

Loss of G9a preserves mutation patterns but increases chromatin accessibility, genomic instability and aggressiveness in skin tumours.

Avgustinova A, Symeonidi A, Castellanos A, Urdiroz-Urricelqui U, Solé-Boldo L, Martín M, Pérez-Rodríguez I, Prats N, Lehner B, Supek F, Benitah SA. Avgustinova A, et al. Among authors: supek f. Nat Cell Biol. 2018 Dec;20(12):1400-1409. doi: 10.1038/s41556-018-0233-x. Epub 2018 Nov 19. Nat Cell Biol. 2018. PMID: 30455462 Free article.

2

Nucleoid-associated proteins affect mutation dynamics in E. coli in a growth phase-specific manner.

Warnecke T, Supek F, Lehner B. Warnecke T, et al. Among authors: supek f. PLoS Comput Biol. 2012;8(12):e1002846. doi: 10.1371/journal.pcbi.1002846. Epub 2012 Dec 20. PLoS Comput Biol. 2012. PMID: 23284284 Free PMC article.

3

Synonymous mutations frequently act as driver mutations in human cancers.

Supek F, Miñana B, Valcárcel J, Gabaldón T, Lehner B. Supek F, et al. Cell. 2014 Mar 13;156(6):1324-1335. doi: 10.1016/j.cell.2014.01.051. Cell. 2014. PMID: 24630730 Free article.

4

Hydroxymethylated cytosines are associated with elevated C to G transversion rates.

Supek F, Lehner B, Hajkova P, Warnecke T. Supek F, et al. PLoS Genet. 2014 Sep 11;10(9):e1004585. doi: 10.1371/journal.pgen.1004585. eCollection 2014 Sep. PLoS Genet. 2014. PMID: 25211471 Free PMC article.

5

Differential DNA mismatch repair underlies mutation rate variation across the human genome.

Supek F, Lehner B. Supek F, et al. Nature. 2015 May 7;521(7550):81-4. doi: 10.1038/nature14173. Epub 2015 Feb 23. Nature. 2015. PMID: 25707793 Free PMC article.

6

MUFFINN: cancer gene discovery via network analysis of somatic mutation data.

Cho A, Shim JE, Kim E, Supek F, Lehner B, Lee I. Cho A, et al. Among authors: supek f. Genome Biol. 2016 Jun 23;17(1):129. doi: 10.1186/s13059-016-0989-x. Genome Biol. 2016. PMID: 27333808 Free PMC article.

7

The rules and impact of nonsense-mediated mRNA decay in human cancers.

Lindeboom RG, Supek F, Lehner B. Lindeboom RG, et al. Among authors: supek f. Nat Genet. 2016 Oct;48(10):1112-8. doi: 10.1038/ng.3664. Epub 2016 Sep 12. Nat Genet. 2016. PMID: 27618451 Free PMC article.

8

Clustered Mutation Signatures Reveal that Error-Prone DNA Repair Targets Mutations to Active Genes.

Supek F, Lehner B. Supek F, et al. Cell. 2017 Jul 27;170(3):534-547.e23. doi: 10.1016/j.cell.2017.07.003. Cell. 2017. PMID: 28753428 Free article.

9

Systematic discovery of germline cancer predisposition genes through the identification of somatic second hits.

Park S, Supek F, Lehner B. Park S, et al. Among authors: supek f. Nat Commun. 2018 Jul 4;9(1):2601. doi: 10.1038/s41467-018-04900-7. Nat Commun. 2018. PMID: 29973584 Free PMC article.

10

Scales and mechanisms of somatic mutation rate variation across the human genome.

Supek F, Lehner B. Supek F, et al. DNA Repair (Amst). 2019 Sep;81:102647. doi: 10.1016/j.dnarep.2019.102647. Epub 2019 Jul 8. DNA Repair (Amst). 2019. PMID: 31307927 Free article. Review.

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