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Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands.
Alshehri OM, Montague S, Watson S, Carter P, Sarker N, Manne BK, Miller JL, Herr AB, Pollitt AY, O'Callaghan CA, Kunapuli S, Arman M, Hughes CE, Watson SP. Alshehri OM, et al. Among authors: herr ab. Biochem J. 2015 Jun 15;468(3):459-73. doi: 10.1042/BJ20150192. Epub 2015 Apr 7. Biochem J. 2015. PMID: 25849538
Structural basis for collagen recognition by the immune receptor OSCAR.
Zhou L, Hinerman JM, Blaszczyk M, Miller JL, Conrady DG, Barrow AD, Chirgadze DY, Bihan D, Farndale RW, Herr AB. Zhou L, et al. Among authors: herr ab. Blood. 2016 Feb 4;127(5):529-37. doi: 10.1182/blood-2015-08-667055. Epub 2015 Nov 9. Blood. 2016. PMID: 26552697 Free PMC article.
Fibrin and D-dimer bind to monomeric GPVI.
Onselaer MB, Hardy AT, Wilson C, Sanchez X, Babar AK, Miller JLC, Watson CN, Watson SK, Bonna A, Philippou H, Herr AB, Mezzano D, Ariëns RAS, Watson SP. Onselaer MB, et al. Among authors: herr ab. Blood Adv. 2017 Aug 15;1(19):1495-1504. doi: 10.1182/bloodadvances.2017007732. eCollection 2017 Aug 22. Blood Adv. 2017. PMID: 29296791 Free PMC article.
Pregnancy enables antibody protection against intracellular infection.
Erickson JJ, Archer-Hartmann S, Yarawsky AE, Miller JLC, Seveau S, Shao TY, Severance AL, Miller-Handley H, Wu Y, Pham G, Wasik BR, Parrish CR, Hu YC, Lau JTY, Azadi P, Herr AB, Way SS. Erickson JJ, et al. Among authors: herr ab. Nature. 2022 Jun;606(7915):769-775. doi: 10.1038/s41586-022-04816-9. Epub 2022 Jun 8. Nature. 2022. PMID: 35676476 Free PMC article.
Immobilized fibrinogen activates human platelets through glycoprotein VI.
Mangin PH, Onselaer MB, Receveur N, Le Lay N, Hardy AT, Wilson C, Sanchez X, Loyau S, Dupuis A, Babar AK, Miller JL, Philippou H, Hughes CE, Herr AB, Ariëns RA, Mezzano D, Jandrot-Perrus M, Gachet C, Watson SP. Mangin PH, et al. Among authors: herr ab. Haematologica. 2018 May;103(5):898-907. doi: 10.3324/haematol.2017.182972. Epub 2018 Feb 22. Haematologica. 2018. PMID: 29472360 Free PMC article.
105 results