Transfer of the amino-terminal nuclear envelope targeting domain of human MX2 converts MX1 into an HIV-1 resistance factor.
Goujon C, Moncorgé O, Bauby H, Doyle T, Barclay WS, Malim MH.
Goujon C, et al.
J Virol. 2014 Aug;88(16):9017-26. doi: 10.1128/JVI.01269-14. Epub 2014 Jun 4.
J Virol. 2014.
PMID: 24899177
Free PMC article.
The myxovirus resistance 2 (MX2) protein of humans has been identified recently as an interferon (IFN)-inducible inhibitor of human immunodeficiency virus type 1 (HIV-1) that acts at a late postentry step of infection to prevent the nuclear accumulation of viral cDNA (C. …
The myxovirus resistance 2 (MX2) protein of humans has been identified recently as an interferon (IFN)-inducible inhibitor of human immunode …