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Page 1
Opioids and GI Motility-Friend or Foe?
Lee AA, Hasler WL. Lee AA, et al. Curr Treat Options Gastroenterol. 2016 Dec;14(4):478-494. doi: 10.1007/s11938-016-0112-0. Curr Treat Options Gastroenterol. 2016. PMID: 27807793 Review.
Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs.
Hens B, Tsume Y, Bermejo M, Paixao P, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Dickens J, Shedden K, Wen B, Wysocki J, Loebenberg R, Lee A, Frances A, Amidon G, Yu A, Benninghoff G, Salehi N, Talattof A, Sun D, Amidon GL. Hens B, et al. Mol Pharm. 2017 Dec 4;14(12):4281-4294. doi: 10.1021/acs.molpharmaceut.7b00426. Epub 2017 Aug 4. Mol Pharm. 2017. PMID: 28737409 Clinical Trial.
Diabetes and the Stomach.
Lee AA, Hasler WL. Lee AA, et al. Curr Treat Options Gastroenterol. 2017 Dec;15(4):441-459. doi: 10.1007/s11938-017-0146-y. Curr Treat Options Gastroenterol. 2017. PMID: 28879488 Review.
In Vivo Dissolution and Systemic Absorption of Immediate Release Ibuprofen in Human Gastrointestinal Tract under Fed and Fasted Conditions.
Koenigsknecht MJ, Baker JR, Wen B, Frances A, Zhang H, Yu A, Zhao T, Tsume Y, Pai MP, Bleske BE, Zhang X, Lionberger R, Lee A, Amidon GL, Hasler WL, Sun D. Koenigsknecht MJ, et al. Mol Pharm. 2017 Dec 4;14(12):4295-4304. doi: 10.1021/acs.molpharmaceut.7b00425. Epub 2017 Oct 5. Mol Pharm. 2017. PMID: 28937221 Free PMC article. Clinical Trial.
Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach.
Paixão P, Bermejo M, Hens B, Tsume Y, Dickens J, Shedden K, Salehi N, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Wysocki J, Wen B, Lee A, Frances A, Amidon GE, Yu A, Benninghoff G, Löbenberg R, Talattof A, Sun D, Amidon GL. Paixão P, et al. Eur J Pharm Biopharm. 2018 Aug;129:162-174. doi: 10.1016/j.ejpb.2018.05.033. Epub 2018 May 29. Eur J Pharm Biopharm. 2018. PMID: 29857136 Free PMC article. Clinical Trial.
Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State.
Paixão P, Bermejo M, Hens B, Tsume Y, Dickens J, Shedden K, Salehi N, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Wysocki J, Wen B, Lee A, Frances A, Amidon GE, Yu A, Benninghoff G, Löbenberg R, Talattof A, Sun D, Amidon GL. Paixão P, et al. Mol Pharm. 2018 Dec 3;15(12):5468-5478. doi: 10.1021/acs.molpharmaceut.8b00736. Epub 2018 Nov 12. Mol Pharm. 2018. PMID: 30417648 Free PMC article. Clinical Trial.
219 results