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Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins.
Serradell MC, Rupil LL, Martino RA, Prucca CG, Carranza PG, Saura A, Fernández EA, Gargantini PR, Tenaglia AH, Petiti JP, Tonelli RR, Reinoso-Vizcaino N, Echenique J, Berod L, Piaggio E, Bellier B, Sparwasser T, Klatzmann D, Luján HD. Serradell MC, et al. Among authors: piaggio e. Nat Commun. 2019 Jan 21;10(1):361. doi: 10.1038/s41467-018-08265-9. Nat Commun. 2019. PMID: 30664644 Free PMC article.
Phase Ib/II trial of tipapkinogene sovacivec, a therapeutic human papillomavirus16-vaccine, in combination with avelumab in patients with advanced human papillomavirus16-positive cancers.
Borcoman E, Lalanne A, Delord JP, Cassier PA, Rolland F, Salas S, Limacher JM, Capitain O, Lantz O, Ekwegbara C, Jeannot E, Cyrta J, Tran-Perennou C, Castel-Ajgal Z, Marret G, Piaggio E, Brandely M, Tavernaro A, Makhloufi H, Bendjama K, Le Tourneau C. Borcoman E, et al. Among authors: piaggio e. Eur J Cancer. 2023 Sep;191:112981. doi: 10.1016/j.ejca.2023.112981. Epub 2023 Jul 11. Eur J Cancer. 2023. PMID: 37506588 Clinical Trial.
Galectin-3 deficiency drives lupus-like disease by promoting spontaneous germinal centers formation via IFN-γ.
Beccaria CG, Amezcua Vesely MC, Fiocca Vernengo F, Gehrau RC, Ramello MC, Tosello Boari J, Gorosito Serrán M, Mucci J, Piaggio E, Campetella O, Acosta Rodríguez EV, Montes CL, Gruppi A. Beccaria CG, et al. Among authors: piaggio e. Nat Commun. 2018 Apr 24;9(1):1628. doi: 10.1038/s41467-018-04063-5. Nat Commun. 2018. PMID: 29691398 Free PMC article.
Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens.
Lynn GM, Sedlik C, Baharom F, Zhu Y, Ramirez-Valdez RA, Coble VL, Tobin K, Nichols SR, Itzkowitz Y, Zaidi N, Gammon JM, Blobel NJ, Denizeau J, de la Rochere P, Francica BJ, Decker B, Maciejewski M, Cheung J, Yamane H, Smelkinson MG, Francica JR, Laga R, Bernstock JD, Seymour LW, Drake CG, Jewell CM, Lantz O, Piaggio E, Ishizuka AS, Seder RA. Lynn GM, et al. Among authors: piaggio e. Nat Biotechnol. 2020 Mar;38(3):320-332. doi: 10.1038/s41587-019-0390-x. Epub 2020 Jan 13. Nat Biotechnol. 2020. PMID: 31932728 Free PMC article.
Blockade of Stat3 oncogene addiction induces cellular senescence and reveals a cell-nonautonomous activity suitable for cancer immunotherapy.
De Martino M, Tkach M, Bruni S, Rocha D, Mercogliano MF, Cenciarini ME, Chervo MF, Proietti CJ, Dingli F, Loew D, Fernández EA, Elizalde PV, Piaggio E, Schillaci R. De Martino M, et al. Among authors: piaggio e. Oncoimmunology. 2020 Jan 29;9(1):1715767. doi: 10.1080/2162402X.2020.1715767. eCollection 2020. Oncoimmunology. 2020. PMID: 32064174 Free PMC article.
Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients.
Núñez NG, Tosello Boari J, Ramos RN, Richer W, Cagnard N, Anderfuhren CD, Niborski LL, Bigot J, Meseure D, De La Rochere P, Milder M, Viel S, Loirat D, Pérol L, Vincent-Salomon A, Sastre-Garau X, Burkhard B, Sedlik C, Lantz O, Amigorena S, Piaggio E. Núñez NG, et al. Among authors: piaggio e. Nat Commun. 2020 Jun 29;11(1):3272. doi: 10.1038/s41467-020-17046-2. Nat Commun. 2020. PMID: 32601304 Free PMC article.
94 results