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Orthogonal Cas9 proteins for RNA-guided gene regulation and editing.
Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM. Esvelt KM, et al. Among authors: mali p. Nat Methods. 2013 Nov;10(11):1116-21. doi: 10.1038/nmeth.2681. Epub 2013 Sep 29. Nat Methods. 2013. PMID: 24076762 Free PMC article.
Engineering and optimising deaminase fusions for genome editing.
Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Yang L, et al. Among authors: mali p. Nat Commun. 2016 Nov 2;7:13330. doi: 10.1038/ncomms13330. Nat Commun. 2016. PMID: 27804970 Free PMC article.
Rapidly evolving homing CRISPR barcodes.
Kalhor R, Mali P, Church GM. Kalhor R, et al. Among authors: mali p. Nat Methods. 2017 Feb;14(2):195-200. doi: 10.1038/nmeth.4108. Epub 2016 Dec 5. Nat Methods. 2017. PMID: 27918539 Free PMC article.
Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.
Shen JP, Zhao D, Sasik R, Luebeck J, Birmingham A, Bojorquez-Gomez A, Licon K, Klepper K, Pekin D, Beckett AN, Sanchez KS, Thomas A, Kuo CC, Du D, Roguev A, Lewis NE, Chang AN, Kreisberg JF, Krogan N, Qi L, Ideker T, Mali P. Shen JP, et al. Among authors: mali p. Nat Methods. 2017 Jun;14(6):573-576. doi: 10.1038/nmeth.4225. Epub 2017 Mar 20. Nat Methods. 2017. PMID: 28319113 Free PMC article.
Genetic interaction mapping in mammalian cells using CRISPR interference.
Du D, Roguev A, Gordon DE, Chen M, Chen SH, Shales M, Shen JP, Ideker T, Mali P, Qi LS, Krogan NJ. Du D, et al. Among authors: mali p. Nat Methods. 2017 Jun;14(6):577-580. doi: 10.1038/nmeth.4286. Epub 2017 May 8. Nat Methods. 2017. PMID: 28481362 Free PMC article.
In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation.
Moreno AM, Fu X, Zhu J, Katrekar D, Shih YV, Marlett J, Cabotaje J, Tat J, Naughton J, Lisowski L, Varghese S, Zhang K, Mali P. Moreno AM, et al. Among authors: mali p. Mol Ther. 2018 Jul 5;26(7):1818-1827. doi: 10.1016/j.ymthe.2018.04.017. Epub 2018 Apr 25. Mol Ther. 2018. PMID: 29754775 Free PMC article.
192 results