Novel series of tunable µOR modulators with enhanced brain penetration for the treatment of opioid use disorder, pain and neuropsychiatric indications.
Nerurkar A, Nguyen T, Wang S, Bhatt U, Li K, Li Y, Ding P, Seidl FJ, Holan M, Lee J, Widjaja T, Wei ZL, Sadlowski C, Sperandio D, McGee LR, Youngblood B, Schwartz N, Gehlert D, Medina JC.
Nerurkar A, et al. Among authors: sadlowski c.
Bioorg Med Chem Lett. 2023 Aug 15;92:129405. doi: 10.1016/j.bmcl.2023.129405. Epub 2023 Jul 5.
Bioorg Med Chem Lett. 2023.
PMID: 37414346
Free PMC article.