Smith BJ - Search Results

1

Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor.

Ahorukomeye P, Disotuar MM, Gajewiak J, Karanth S, Watkins M, Robinson SD, Flórez Salcedo P, Smith NA, Smith BJ, Schlegel A, Forbes BE, Olivera B, Hung-Chieh Chou D, Safavi-Hemami H. Ahorukomeye P, et al. Among authors: smith bj, smith na. Elife. 2019 Feb 12;8:e41574. doi: 10.7554/eLife.41574. Elife. 2019. PMID: 30747102 Free PMC article.

2

Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels.

Bulaj G, West PJ, Garrett JE, Watkins M, Zhang MM, Norton RS, Smith BJ, Yoshikami D, Olivera BM. Bulaj G, et al. Among authors: smith bj. Biochemistry. 2005 May 17;44(19):7259-65. doi: 10.1021/bi0473408. Biochemistry. 2005. PMID: 15882064

3

Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels.

Zhang MM, Fiedler B, Green BR, Catlin P, Watkins M, Garrett JE, Smith BJ, Yoshikami D, Olivera BM, Bulaj G. Zhang MM, et al. Among authors: smith bj. Biochemistry. 2006 Mar 21;45(11):3723-32. doi: 10.1021/bi052162j. Biochemistry. 2006. PMID: 16533055

4

Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity.

Green BR, Catlin P, Zhang MM, Fiedler B, Bayudan W, Morrison A, Norton RS, Smith BJ, Yoshikami D, Olivera BM, Bulaj G. Green BR, et al. Among authors: smith bj. Chem Biol. 2007 Apr;14(4):399-407. doi: 10.1016/j.chembiol.2007.02.009. Chem Biol. 2007. PMID: 17462575

5

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

Zhang MM, Green BR, Catlin P, Fiedler B, Azam L, Chadwick A, Terlau H, McArthur JR, French RJ, Gulyas J, Rivier JE, Smith BJ, Norton RS, Olivera BM, Yoshikami D, Bulaj G. Zhang MM, et al. Among authors: smith bj. J Biol Chem. 2007 Oct 19;282(42):30699-706. doi: 10.1074/jbc.M704616200. Epub 2007 Aug 27. J Biol Chem. 2007. PMID: 17724025 Free article.

6

Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies.

Iyer S, Anwari K, Alsop AE, Yuen WS, Huang DC, Carroll J, Smith NA, Smith BJ, Dewson G, Kluck RM. Iyer S, et al. Among authors: smith bj, smith na. Nat Commun. 2016 May 24;7:11734. doi: 10.1038/ncomms11734. Nat Commun. 2016. PMID: 27217060 Free PMC article.

7

Insulin Mimetic Peptide Disrupts the Primary Binding Site of the Insulin Receptor.

Lawrence CF, Margetts MB, Menting JG, Smith NA, Smith BJ, Ward CW, Lawrence MC. Lawrence CF, et al. Among authors: smith bj, smith na. J Biol Chem. 2016 Jul 22;291(30):15473-81. doi: 10.1074/jbc.M116.732180. Epub 2016 Jun 8. J Biol Chem. 2016. PMID: 27281820 Free PMC article.

8

A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.

Menting JG, Gajewiak J, MacRaild CA, Chou DH, Disotuar MM, Smith NA, Miller C, Erchegyi J, Rivier JE, Olivera BM, Forbes BE, Smith BJ, Norton RS, Safavi-Hemami H, Lawrence MC. Menting JG, et al. Among authors: smith bj, smith na. Nat Struct Mol Biol. 2016 Oct;23(10):916-920. doi: 10.1038/nsmb.3292. Epub 2016 Sep 12. Nat Struct Mol Biol. 2016. PMID: 27617429

9

Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding.

Glidden MD, Yang Y, Smith NA, Phillips NB, Carr K, Wickramasinghe NP, Ismail-Beigi F, Lawrence MC, Smith BJ, Weiss MA. Glidden MD, et al. Among authors: smith bj, smith na. J Biol Chem. 2018 Jan 5;293(1):69-88. doi: 10.1074/jbc.M117.808667. Epub 2017 Nov 7. J Biol Chem. 2018. PMID: 29114034 Free PMC article.

10

Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.

Lee EF, Smith NA, Soares da Costa TP, Meftahi N, Yao S, Harris TJ, Tran S, Pettikiriarachchi A, Perugini MA, Keizer DW, Evangelista M, Smith BJ, Fairlie WD. Lee EF, et al. Among authors: smith bj, smith na. Autophagy. 2019 May;15(5):785-795. doi: 10.1080/15548627.2018.1564557. Epub 2019 Jan 9. Autophagy. 2019. PMID: 30626284 Free PMC article.

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