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Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties.
Chen X, Wilson RM, Kubo H, Berretta RM, Harris DM, Zhang X, Jaleel N, MacDonnell SM, Bearzi C, Tillmanns J, Trofimova I, Hosoda T, Mosna F, Cribbs L, Leri A, Kajstura J, Anversa P, Houser SR. Chen X, et al. Among authors: zhang x. Circ Res. 2007 Mar 2;100(4):536-44. doi: 10.1161/01.RES.0000259560.39234.99. Epub 2007 Feb 1. Circ Res. 2007. PMID: 17272809
Enhanced basal contractility but reduced excitation-contraction coupling efficiency and beta-adrenergic reserve of hearts with increased Cav1.2 activity.
Tang M, Zhang X, Li Y, Guan Y, Ai X, Szeto C, Nakayama H, Zhang H, Ge S, Molkentin JD, Houser SR, Chen X. Tang M, et al. Among authors: zhang x, zhang h. Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H519-28. doi: 10.1152/ajpheart.00265.2010. Epub 2010 Jun 11. Am J Physiol Heart Circ Physiol. 2010. PMID: 20543081 Free PMC article.
Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy.
Chen X, Nakayama H, Zhang X, Ai X, Harris DM, Tang M, Zhang H, Szeto C, Stockbower K, Berretta RM, Eckhart AD, Koch WJ, Molkentin JD, Houser SR. Chen X, et al. Among authors: zhang x, zhang h. J Mol Cell Cardiol. 2011 Mar;50(3):460-70. doi: 10.1016/j.yjmcc.2010.11.012. Epub 2010 Nov 25. J Mol Cell Cardiol. 2011. PMID: 21111744 Free PMC article.
Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling.
Zhang X, Szeto C, Gao E, Tang M, Jin J, Fu Q, Makarewich C, Ai X, Li Y, Tang A, Wang J, Gao H, Wang F, Ge XJ, Kunapuli SP, Zhou L, Zeng C, Xiang KY, Chen X. Zhang X, et al. Circ Res. 2013 Feb 1;112(3):498-509. doi: 10.1161/CIRCRESAHA.112.273896. Epub 2012 Oct 25. Circ Res. 2013. PMID: 23104882 Free PMC article.
Reduced Myocardial Reserve in Young X-Linked Muscular Dystrophy Mice Diagnosed by Two-Dimensional Strain Analysis Combined with Stress Echocardiography.
Li Z, Li Y, Zhang L, Zhang X, Sullivan R, Ai X, Szeto C, Cai A, Liu L, Xiao W, Li Q, Ge S, Chen X. Li Z, et al. Among authors: zhang l, zhang x. J Am Soc Echocardiogr. 2017 Aug;30(8):815-827.e9. doi: 10.1016/j.echo.2017.03.009. Epub 2017 May 13. J Am Soc Echocardiogr. 2017. PMID: 28511858 Free PMC article.
Cardiomyocyte PKA Ablation Enhances Basal Contractility While Eliminates Cardiac β-Adrenergic Response Without Adverse Effects on the Heart.
Zhang Y, Wang WE, Zhang X, Li Y, Chen B, Liu C, Ai X, Zhang X, Tian Y, Zhang C, Tang M, Szeto C, Hua X, Xie M, Zeng C, Wu Y, Zhou L, Zhu W, Yu D, Houser SR, Chen X. Zhang Y, et al. Among authors: zhang c, zhang x. Circ Res. 2019 Jun 7;124(12):1760-1777. doi: 10.1161/CIRCRESAHA.118.313417. Epub 2019 Apr 15. Circ Res. 2019. PMID: 30982412
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