Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol.
Wang L, Smith J, Breton C, Clark P, Zhang J, Ying L, Che Y, Lape J, Bell P, Calcedo R, Buza EL, Saveliev A, Bartsevich VV, He Z, White J, Li M, Jantz D, Wilson JM.
Wang L, et al. Among authors: saveliev a.
Nat Biotechnol. 2018 Sep;36(8):717-725. doi: 10.1038/nbt.4182. Epub 2018 Jul 9.
Nat Biotechnol. 2018.
PMID: 29985478