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Cardiomyocyte PKA Ablation Enhances Basal Contractility While Eliminates Cardiac β-Adrenergic Response Without Adverse Effects on the Heart.
Zhang Y, Wang WE, Zhang X, Li Y, Chen B, Liu C, Ai X, Zhang X, Tian Y, Zhang C, Tang M, Szeto C, Hua X, Xie M, Zeng C, Wu Y, Zhou L, Zhu W, Yu D, Houser SR, Chen X. Zhang Y, et al. Among authors: chen b, chen x. Circ Res. 2019 Jun 7;124(12):1760-1777. doi: 10.1161/CIRCRESAHA.118.313417. Epub 2019 Apr 15. Circ Res. 2019. PMID: 30982412
T-tubule remodeling during transition from hypertrophy to heart failure.
Wei S, Guo A, Chen B, Kutschke W, Xie YP, Zimmerman K, Weiss RM, Anderson ME, Cheng H, Song LS. Wei S, et al. Among authors: chen b. Circ Res. 2010 Aug 20;107(4):520-31. doi: 10.1161/CIRCRESAHA.109.212324. Epub 2010 Jun 24. Circ Res. 2010. PMID: 20576937 Free PMC article.
PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes.
Wu CY, Jia Z, Wang W, Ballou LM, Jiang YP, Chen B, Mathias RT, Cohen IS, Song LS, Entcheva E, Lin RZ. Wu CY, et al. Among authors: chen b. PLoS One. 2011;6(9):e24404. doi: 10.1371/journal.pone.0024404. Epub 2011 Sep 2. PLoS One. 2011. PMID: 21912691 Free PMC article.
In situ confocal imaging in intact heart reveals stress-induced Ca(2+) release variability in a murine catecholaminergic polymorphic ventricular tachycardia model of type 2 ryanodine receptor(R4496C+/-) mutation.
Chen B, Guo A, Gao Z, Wei S, Xie YP, Chen SR, Anderson ME, Song LS. Chen B, et al. Among authors: chen sr. Circ Arrhythm Electrophysiol. 2012 Aug 1;5(4):841-9. doi: 10.1161/CIRCEP.111.969733. Epub 2012 Jun 21. Circ Arrhythm Electrophysiol. 2012. PMID: 22722659 Free PMC article.
Emerging mechanisms of T-tubule remodelling in heart failure.
Guo A, Zhang C, Wei S, Chen B, Song LS. Guo A, et al. Among authors: chen b. Cardiovasc Res. 2013 May 1;98(2):204-15. doi: 10.1093/cvr/cvt020. Epub 2013 Feb 7. Cardiovasc Res. 2013. PMID: 23393229 Free PMC article. Review.
Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation.
Purohit A, Rokita AG, Guan X, Chen B, Koval OM, Voigt N, Neef S, Sowa T, Gao Z, Luczak ED, Stefansdottir H, Behunin AC, Li N, El-Accaoui RN, Yang B, Swaminathan PD, Weiss RM, Wehrens XH, Song LS, Dobrev D, Maier LS, Anderson ME. Purohit A, et al. Among authors: chen b. Circulation. 2013 Oct 15;128(16):1748-57. doi: 10.1161/CIRCULATIONAHA.113.003313. Epub 2013 Sep 12. Circulation. 2013. PMID: 24030498 Free PMC article.
Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.
Zhang C, Chen B, Guo A, Zhu Y, Miller JD, Gao S, Yuan C, Kutschke W, Zimmerman K, Weiss RM, Wehrens XH, Hong J, Johnson FL, Santana LF, Anderson ME, Song LS. Zhang C, et al. Among authors: chen b. Circulation. 2014 Apr 29;129(17):1742-50. doi: 10.1161/CIRCULATIONAHA.113.008452. Epub 2014 Feb 11. Circulation. 2014. PMID: 24519927 Free PMC article.
Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias.
Zhang X, Ai X, Nakayama H, Chen B, Harris DM, Tang M, Xie Y, Szeto C, Li Y, Li Y, Zhang H, Eckhart AD, Koch WJ, Molkentin JD, Chen X. Zhang X, et al. Among authors: chen b, chen x. Basic Res Cardiol. 2016 Jan;111(1):4. doi: 10.1007/s00395-015-0523-4. Epub 2015 Nov 26. Basic Res Cardiol. 2016. PMID: 26611208 Free PMC article.
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