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A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity.
Karnell JL, Albulescu M, Drabic S, Wang L, Moate R, Baca M, Oganesyan V, Gunsior M, Thisted T, Yan L, Li J, Xiong X, Eck SC, de Los Reyes M, Yusuf I, Streicher K, Müller-Ladner U, Howe D, Ettinger R, Herbst R, Drappa J. Karnell JL, et al. Sci Transl Med. 2019 Apr 24;11(489):eaar6584. doi: 10.1126/scitranslmed.aar6584. Sci Transl Med. 2019. PMID: 31019027
CD19 and CD32b differentially regulate human B cell responsiveness.
Karnell JL, Dimasi N, Karnell FG 3rd, Fleming R, Kuta E, Wilson M, Wu H, Gao C, Herbst R, Ettinger R. Karnell JL, et al. Among authors: karnell fg 3rd. J Immunol. 2014 Feb 15;192(4):1480-90. doi: 10.4049/jimmunol.1301361. Epub 2014 Jan 17. J Immunol. 2014. PMID: 24442430 Free PMC article.
Self-reactive IgE exacerbates interferon responses associated with autoimmunity.
Henault J, Riggs JM, Karnell JL, Liarski VM, Li J, Shirinian L, Xu L, Casey KA, Smith MA, Khatry DB, Izhak L, Clarke L, Herbst R, Ettinger R, Petri M, Clark MR, Mustelin T, Kolbeck R, Sanjuan MA. Henault J, et al. Among authors: karnell jl. Nat Immunol. 2016 Feb;17(2):196-203. doi: 10.1038/ni.3326. Epub 2015 Dec 21. Nat Immunol. 2016. PMID: 26692173 Free PMC article.
Autoimmune manifestations in aged mice arise from early-life immune dysregulation.
Mahmoud TI, Wang J, Karnell JL, Wang Q, Wang S, Naiman B, Gross P, Brohawn PZ, Morehouse C, Aoyama J, Wasserfall C, Carter L, Atkinson MA, Serreze DV, Braley-Mullen H, Mustelin T, Kolbeck R, Herbst R, Ettinger R. Mahmoud TI, et al. Among authors: karnell jl. Sci Transl Med. 2016 Oct 19;8(361):361ra137. doi: 10.1126/scitranslmed.aag0367. Sci Transl Med. 2016. PMID: 27798262 Free PMC article.
Role of CD11c+ T-bet+ B cells in human health and disease.
Karnell JL, Kumar V, Wang J, Wang S, Voynova E, Ettinger R. Karnell JL, et al. Cell Immunol. 2017 Nov;321:40-45. doi: 10.1016/j.cellimm.2017.05.008. Epub 2017 Jul 11. Cell Immunol. 2017. PMID: 28756897 Free article. Review.
22 results