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NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.
Reynolds N, Latos P, Hynes-Allen A, Loos R, Leaford D, O'Shaughnessy A, Mosaku O, Signolet J, Brennecke P, Kalkan T, Costello I, Humphreys P, Mansfield W, Nakagawa K, Strouboulis J, Behrens A, Bertone P, Hendrich B. Reynolds N, et al. Cell Stem Cell. 2012 May 4;10(5):583-94. doi: 10.1016/j.stem.2012.02.020. Cell Stem Cell. 2012. PMID: 22560079 Free PMC article.
The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression.
Bornelöv S, Reynolds N, Xenophontos M, Gharbi S, Johnstone E, Floyd R, Ralser M, Signolet J, Loos R, Dietmann S, Bertone P, Hendrich B. Bornelöv S, et al. Among authors: reynolds n. Mol Cell. 2018 Jul 5;71(1):56-72.e4. doi: 10.1016/j.molcel.2018.06.003. Epub 2018 Jun 28. Mol Cell. 2018. PMID: 30008319 Free PMC article.
Enhancer-promoter interactions are reconfigured through the formation of long-range multiway hubs as mouse ES cells exit pluripotency.
Lando D, Ma X, Cao Y, Jartseva A, Stevens TJ, Boucher W, Reynolds N, Montibus B, Hall D, Lackner A, Ragheb R, Leeb M, Hendrich BD, Laue ED. Lando D, et al. Among authors: reynolds n. Mol Cell. 2024 Apr 18;84(8):1406-1421.e8. doi: 10.1016/j.molcel.2024.02.015. Epub 2024 Mar 14. Mol Cell. 2024. PMID: 38490199 Free PMC article.
698 results