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Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease.
Sofi MH, Wu Y, Schutt SD, Dai M, Daenthanasanmak A, Heinrichs Voss J, Nguyen H, Bastian D, Iamsawat S, Selvam SP, Liu C, Maulik N, Ogretmen B, Jin J, Mehrotra S, Yu XZ. Sofi MH, et al. Among authors: selvam sp. J Clin Invest. 2019 May 2;129(7):2760-2774. doi: 10.1172/JCI122899. J Clin Invest. 2019. PMID: 31045571 Free PMC article.
Thioredoxin-1 improves the immunometabolic phenotype of antitumor T cells.
Chakraborty P, Chatterjee S, Kesarwani P, Thyagarajan K, Iamsawat S, Dalheim A, Nguyen H, Selvam SP, Nasarre P, Scurti G, Hardiman G, Maulik N, Ball L, Gangaraju V, Rubinstein MP, Klauber-DeMore N, Hill EG, Ogretmen B, Yu XZ, Nishimura MI, Mehrotra S. Chakraborty P, et al. Among authors: selvam sp. J Biol Chem. 2019 Jun 7;294(23):9198-9212. doi: 10.1074/jbc.RA118.006753. Epub 2019 Apr 10. J Biol Chem. 2019. PMID: 30971427 Free PMC article.
Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity.
Chakraborty P, Vaena SG, Thyagarajan K, Chatterjee S, Al-Khami A, Selvam SP, Nguyen H, Kang I, Wyatt MW, Baliga U, Hedley Z, Ngang RN, Guo B, Beeson GC, Husain S, Paulos CM, Beeson CC, Zilliox MJ, Hill EG, Mehrotra M, Yu XZ, Ogretmen B, Mehrotra S. Chakraborty P, et al. Among authors: selvam sp. Cell Rep. 2019 Aug 13;28(7):1879-1893.e7. doi: 10.1016/j.celrep.2019.07.044. Cell Rep. 2019. PMID: 31412253 Free PMC article.
CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.
Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP, Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI, Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S. Chatterjee S, et al. Among authors: selvam sp. Cell Metab. 2018 Jan 9;27(1):85-100.e8. doi: 10.1016/j.cmet.2017.10.006. Epub 2017 Nov 9. Cell Metab. 2018. PMID: 29129787 Free PMC article.
Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A.
Salas A, Ponnusamy S, Senkal CE, Meyers-Needham M, Selvam SP, Saddoughi SA, Apohan E, Sentelle RD, Smith C, Gault CR, Obeid LM, El-Shewy HM, Oaks J, Santhanam R, Marcucci G, Baran Y, Mahajan S, Fernandes D, Stuart R, Perrotti D, Ogretmen B. Salas A, et al. Among authors: selvam sp. Blood. 2011 Jun 2;117(22):5941-52. doi: 10.1182/blood-2010-08-300772. Epub 2011 Apr 28. Blood. 2011. PMID: 21527515 Free PMC article.
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy.
Sentelle RD, Senkal CE, Jiang W, Ponnusamy S, Gencer S, Selvam SP, Ramshesh VK, Peterson YK, Lemasters JJ, Szulc ZM, Bielawski J, Ogretmen B. Sentelle RD, et al. Among authors: selvam sp. Nat Chem Biol. 2012 Oct;8(10):831-8. doi: 10.1038/nchembio.1059. Nat Chem Biol. 2012. PMID: 22922758 Free PMC article.
20 results