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Page 1
Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2-interacting protein.
Kotla S, Vu HT, Ko KA, Wang Y, Imanishi M, Heo KS, Fujii Y, Thomas TN, Gi YJ, Mazhar H, Paez-Mayorga J, Shin JH, Tao Y, Giancursio CJ, Medina JL, Taunton J, Lusis AJ, Cooke JP, Fujiwara K, Le NT, Abe JI. Kotla S, et al. Among authors: heo ks. JCI Insight. 2019 May 2;4(9):e124867. doi: 10.1172/jci.insight.124867. eCollection 2019 May 2. JCI Insight. 2019. PMID: 31045573 Free PMC article.
Shear stress and atherosclerosis.
Heo KS, Fujiwara K, Abe J. Heo KS, et al. Mol Cells. 2014 Jun;37(6):435-40. doi: 10.14348/molcells.2014.0078. Epub 2014 Apr 30. Mol Cells. 2014. PMID: 24781409 Free PMC article. Review.
Senescent Phenotype Induced by p90RSK-NRF2 Signaling Sensitizes Monocytes and Macrophages to Oxidative Stress in HIV-Positive Individuals.
Singh MV, Kotla S, Le NT, Ae Ko K, Heo KS, Wang Y, Fujii Y, Thi Vu H, McBeath E, Thomas TN, Jin Gi Y, Tao Y, Medina JL, Taunton J, Carson N, Dogra V, Doyley MM, Tyrell A, Lu W, Qiu X, Stirpe NE, Gates KJ, Hurley C, Fujiwara K, Maggirwar SB, Schifitto G, Abe JI. Singh MV, et al. Among authors: heo ks. Circulation. 2019 Feb 26;139(9):1199-1216. doi: 10.1161/CIRCULATIONAHA.118.036232. Circulation. 2019. PMID: 30586719 Free PMC article. Clinical Trial.
Disturbed flow-induced FAK K152 SUMOylation initiates the formation of pro-inflammation positive feedback loop by inducing reactive oxygen species production in endothelial cells.
Velatooru LR, Abe RJ, Imanishi M, Gi YJ, Ko KA, Heo KS, Fujiwara K, Le NT, Kotla S. Velatooru LR, et al. Among authors: heo ks. Free Radic Biol Med. 2021 Dec;177:404-418. doi: 10.1016/j.freeradbiomed.2021.09.023. Epub 2021 Oct 5. Free Radic Biol Med. 2021. PMID: 34619327 Free PMC article.
A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis.
Le NT, Heo KS, Takei Y, Lee H, Woo CH, Chang E, McClain C, Hurley C, Wang X, Li F, Xu H, Morrell C, Sullivan MA, Cohen MS, Serafimova IM, Taunton J, Fujiwara K, Abe J. Le NT, et al. Among authors: heo ks. Circulation. 2013 Jan 29;127(4):486-99. doi: 10.1161/CIRCULATIONAHA.112.116988. Epub 2012 Dec 14. Circulation. 2013. PMID: 23243209 Free PMC article.
83 results