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Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma.
Bollard J, Miguela V, Ruiz de Galarreta M, Venkatesh A, Bian CB, Roberto MP, Tovar V, Sia D, Molina-Sánchez P, Nguyen CB, Nakagawa S, Llovet JM, Hoshida Y, Lujambio A. Bollard J, et al. Among authors: ruiz de galarreta m. Gut. 2017 Jul;66(7):1286-1296. doi: 10.1136/gutjnl-2016-312268. Epub 2016 Nov 14. Gut. 2017. PMID: 27849562 Free PMC article.
Therapeutic editing of hepatocyte genome in vivo.
Ruiz de Galarreta M, Lujambio A. Ruiz de Galarreta M, et al. J Hepatol. 2017 Oct;67(4):818-828. doi: 10.1016/j.jhep.2017.05.012. Epub 2017 May 17. J Hepatol. 2017. PMID: 28527665 Review.
DNA sensing in senescence.
Ruiz de Galarreta M, Lujambio A. Ruiz de Galarreta M, et al. Nat Cell Biol. 2017 Aug 31;19(9):1008-1009. doi: 10.1038/ncb3603. Nat Cell Biol. 2017. PMID: 28855731
Cell type-specific pharmacological kinase inhibition for cancer chemoprevention.
Deshmukh M, Nakagawa S, Higashi T, Vincek A, Venkatesh A, Ruiz de Galarreta M, Koh AP, Goossens N, Hirschfield H, Bian CB, Fujiwara N, Ono A, Hoshida H, El-Abtah M, Ahmad NB, Lujambio A, Sanchez R, Fuchs BC, Poelstra K, Prakash J, Hoshida Y; Precision Liver Cancer Prevention Consortium. Deshmukh M, et al. Among authors: ruiz de galarreta m. Nanomedicine. 2018 Feb;14(2):317-325. doi: 10.1016/j.nano.2017.11.004. Epub 2017 Nov 20. Nanomedicine. 2018. PMID: 29157977 Free PMC article.
Erratum: DNA sensing in senescence.
Ruiz de Galarreta M, Lujambio A. Ruiz de Galarreta M, et al. Nat Cell Biol. 2017 Nov 29;19(12):1441. doi: 10.1038/ncb3644. Nat Cell Biol. 2017. PMID: 29184173
β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma.
Ruiz de Galarreta M, Bresnahan E, Molina-Sánchez P, Lindblad KE, Maier B, Sia D, Puigvehi M, Miguela V, Casanova-Acebes M, Dhainaut M, Villacorta-Martin C, Singhi AD, Moghe A, von Felden J, Tal Grinspan L, Wang S, Kamphorst AO, Monga SP, Brown BD, Villanueva A, Llovet JM, Merad M, Lujambio A. Ruiz de Galarreta M, et al. Cancer Discov. 2019 Aug;9(8):1124-1141. doi: 10.1158/2159-8290.CD-19-0074. Epub 2019 Jun 11. Cancer Discov. 2019. PMID: 31186238 Free PMC article.
Phenotype-Based Screens with Conformation-Specific Inhibitors Reveal p38 Gamma and Delta as Targets for HCC Polypharmacology.
Yu JX, Craig AJ, Duffy ME, Villacorta-Martin C, Miguela V, Ruiz de Galarreta M, Scopton AP, Silber L, Maldonado AY, Rialdi A, Guccione E, Lujambio A, Villanueva A, Dar AC. Yu JX, et al. Among authors: ruiz de galarreta m. Mol Cancer Ther. 2019 Sep;18(9):1506-1519. doi: 10.1158/1535-7163.MCT-18-0571. Epub 2019 Jun 18. Mol Cancer Ther. 2019. PMID: 31213506 Free PMC article.
Genetic Modification of CD8+ T Cells to Express EGFR: Potential Application for Adoptive T Cell Therapies.
Lozano T, Chocarro S, Martin C, Lasarte-Cia A, Del Valle C, Gorraiz M, Sarrión P, Ruiz de Galarreta M, Lujambio A, Hervás-Stubbs S, Sarobe P, Casares N, Lasarte JJ. Lozano T, et al. Among authors: ruiz de galarreta m. Front Immunol. 2019 Dec 20;10:2990. doi: 10.3389/fimmu.2019.02990. eCollection 2019. Front Immunol. 2019. PMID: 31921216 Free PMC article.
Mouse Models of Oncoimmunology in Hepatocellular Carcinoma.
Bresnahan E, Lindblad KE, Ruiz de Galarreta M, Lujambio A. Bresnahan E, et al. Among authors: ruiz de galarreta m. Clin Cancer Res. 2020 Oct 15;26(20):5276-5286. doi: 10.1158/1078-0432.CCR-19-2923. Epub 2020 Apr 23. Clin Cancer Res. 2020. PMID: 32327473 Free PMC article. Review.
24 results