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Neuropeptide 26RFa (QRFP) is a key regulator of glucose homeostasis and its activity is markedly altered in obese/hyperglycemic mice.
Prévost G, Arabo A, Le Solliec MA, Bons J, Picot M, Maucotel J, Berrahmoune H, El Mehdi M, Cherifi S, Benani A, Nédélec E, Coëffier M, Leprince J, Nordqvist A, Brunel V, Déchelotte P, Lefebvre H, Anouar Y, Chartrel N. Prévost G, et al. Among authors: picot m. Am J Physiol Endocrinol Metab. 2019 Jul 1;317(1):E147-E157. doi: 10.1152/ajpendo.00540.2018. Epub 2019 May 14. Am J Physiol Endocrinol Metab. 2019. PMID: 31084498 Free article.
Hypothalamic Neuropeptide 26RFa Acts as an Incretin to Regulate Glucose Homeostasis.
Prévost G, Jeandel L, Arabo A, Coëffier M, El Ouahli M, Picot M, Alexandre D, Gobet F, Leprince J, Berrahmoune H, Déchelotte P, Malagon M, Bonner C, Kerr-Conte J, Chigr F, Lefebvre H, Anouar Y, Chartrel N. Prévost G, et al. Among authors: picot m. Diabetes. 2015 Aug;64(8):2805-16. doi: 10.2337/db14-1864. Epub 2015 Apr 9. Diabetes. 2015. PMID: 25858563
Design, Synthesis, Molecular Dynamics Simulation, and Functional Evaluation of a Novel Series of 26RFa Peptide Analogues Containing a Mono- or Polyalkyl Guanidino Arginine Derivative.
Alim K, Lefranc B, Sopkova-de Oliveira Santos J, Dubessy C, Picot M, Boutin JA, Vaudry H, Chartrel N, Vaudry D, Chuquet J, Leprince J. Alim K, et al. Among authors: picot m. J Med Chem. 2018 Nov 21;61(22):10185-10197. doi: 10.1021/acs.jmedchem.8b01332. Epub 2018 Nov 7. J Med Chem. 2018. PMID: 30358997
Glucose homeostasis is impaired in mice deficient in the neuropeptide 26RFa (QRFP).
El-Mehdi M, Takhlidjt S, Khiar F, Prévost G, do Rego JL, do Rego JC, Benani A, Nedelec E, Godefroy D, Arabo A, Lefranc B, Leprince J, Anouar Y, Chartrel N, Picot M. El-Mehdi M, et al. Among authors: picot m. BMJ Open Diabetes Res Care. 2020 Feb;8(1):e000942. doi: 10.1136/bmjdrc-2019-000942. BMJ Open Diabetes Res Care. 2020. PMID: 32114486 Free PMC article.
379 results