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201 results

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Page 1
A novel and potent brain penetrant inhibitor of extracellular vesicle release.
Rojas C, Sala M, Thomas AG, Datta Chaudhuri A, Yoo SW, Li Z, Dash RP, Rais R, Haughey NJ, Nencka R, Slusher B. Rojas C, et al. Among authors: yoo sw. Br J Pharmacol. 2019 Oct;176(19):3857-3870. doi: 10.1111/bph.14789. Epub 2019 Sep 4. Br J Pharmacol. 2019. PMID: 31273753 Free PMC article.
Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties.
Figuera-Losada M, Stathis M, Dorskind JM, Thomas AG, Bandaru VV, Yoo SW, Westwood NJ, Rogers GW, McArthur JC, Haughey NJ, Slusher BS, Rojas C. Figuera-Losada M, et al. Among authors: yoo sw. PLoS One. 2015 May 26;10(5):e0124481. doi: 10.1371/journal.pone.0124481. eCollection 2015. PLoS One. 2015. PMID: 26010541 Free PMC article.
Pharmacokinetics of Intranasal versus Subcutaneous Insulin in the Mouse.
Nedelcovych MT, Gadiano AJ, Wu Y, Manning AA, Thomas AG, Khuder SS, Yoo SW, Xu J, McArthur JC, Haughey NJ, Volsky DJ, Rais R, Slusher BS. Nedelcovych MT, et al. Among authors: yoo sw. ACS Chem Neurosci. 2018 Apr 18;9(4):809-816. doi: 10.1021/acschemneuro.7b00434. Epub 2018 Jan 4. ACS Chem Neurosci. 2018. PMID: 29257872 Free PMC article.
DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.
Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer M, Slusher BS. Rojas C, et al. Among authors: yoo sw. Sci Rep. 2018 Dec 7;8(1):17715. doi: 10.1038/s41598-018-36144-2. Sci Rep. 2018. PMID: 30531925 Free PMC article.
Inhibition of neutral sphingomyelinase 2 promotes remyelination.
Yoo SW, Agarwal A, Smith MD, Khuder SS, Baxi EG, Thomas AG, Rojas C, Moniruzzaman M, Slusher BS, Bergles DE, Calabresi PA, Haughey NJ. Yoo SW, et al. Sci Adv. 2020 Oct 2;6(40):eaba5210. doi: 10.1126/sciadv.aba5210. Print 2020 Oct. Sci Adv. 2020. PMID: 33008902 Free PMC article.
Astrocytes deliver CK1 to neurons via extracellular vesicles in response to inflammation promoting the translation and amyloidogenic processing of APP.
Li Z, Moniruzzaman M, Dastgheyb RM, Yoo SW, Wang M, Hao H, Liu J, Casaccia P, Nogueras-Ortiz C, Kapogiannis D, Slusher BS, Haughey NJ. Li Z, et al. Among authors: yoo sw. J Extracell Vesicles. 2020 Dec;10(2):e12035. doi: 10.1002/jev2.12035. Epub 2020 Dec 31. J Extracell Vesicles. 2020. PMID: 33408815 Free PMC article.
201 results