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Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes.
Muramatsu S, Fujimoto K, Ikeguchi K, Shizuma N, Kawasaki K, Ono F, Shen Y, Wang L, Mizukami H, Kume A, Matsumura M, Nagatsu I, Urano F, Ichinose H, Nagatsu T, Terao K, Nakano I, Ozawa K. Muramatsu S, et al. Among authors: kume a. Hum Gene Ther. 2002 Feb 10;13(3):345-54. doi: 10.1089/10430340252792486. Hum Gene Ther. 2002. PMID: 11860702
Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis.
Wang LJ, Lu YY, Muramatsu S, Ikeguchi K, Fujimoto K, Okada T, Mizukami H, Matsushita T, Hanazono Y, Kume A, Nagatsu T, Ozawa K, Nakano I. Wang LJ, et al. Among authors: kume a. J Neurosci. 2002 Aug 15;22(16):6920-8. doi: 10.1523/JNEUROSCI.22-16-06920.2002. J Neurosci. 2002. PMID: 12177190 Free PMC article.
Introduction of the green fluorescent protein gene into hematopoietic stem cells results in prolonged discrepancy of in vivo transduction levels between bone marrow progenitors and peripheral blood cells in nonhuman primates.
Hanazono Y, Terao K, Shibata H, Nagashima T, Ageyama N, Asano T, Ueda Y, Kato I, Kume A, Hasegawa M, Ozawa K. Hanazono Y, et al. Among authors: kume a. J Gene Med. 2002 Sep-Oct;4(5):470-7. doi: 10.1002/jgm.307. J Gene Med. 2002. PMID: 12221639
311 results