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BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis.
Huang K, O'Neill KL, Li J, Zhou W, Han N, Pang X, Wu W, Struble L, Borgstahl G, Liu Z, Zhang L, Luo X. Huang K, et al. Among authors: luo x. Cell Res. 2019 Nov;29(11):942-952. doi: 10.1038/s41422-019-0231-y. Epub 2019 Sep 24. Cell Res. 2019. PMID: 31551537 Free PMC article.
Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition.
Roca-Portoles A, Rodriguez-Blanco G, Sumpton D, Cloix C, Mullin M, Mackay GM, O'Neill K, Lemgruber L, Luo X, Tait SWG. Roca-Portoles A, et al. Among authors: luo x. Cell Death Dis. 2020 Aug 13;11(8):616. doi: 10.1038/s41419-020-02867-2. Cell Death Dis. 2020. PMID: 32792521 Free PMC article.
Diverse functions of cytochrome c in cell death and disease.
Zhou Z, Arroum T, Luo X, Kang R, Lee YJ, Tang D, Hüttemann M, Song X. Zhou Z, et al. Among authors: luo x. Cell Death Differ. 2024 Apr;31(4):387-404. doi: 10.1038/s41418-024-01284-8. Epub 2024 Mar 23. Cell Death Differ. 2024. PMID: 38521844 Review.
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