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N4-Substituted Piperazinyl Norfloxacin Derivatives with Broad-Spectrum Activity and Multiple Mechanisms on Gyrase, Topoisomerase IV, and Bacterial Cell Wall Synthesis.
Kamal El-Sagheir AM, Abdelmesseh Nekhala I, Abd El-Gaber MK, Aboraia AS, Persson J, Schäfer AB, Wenzel M, Omar FA. Kamal El-Sagheir AM, et al. Among authors: schafer ab. ACS Bio Med Chem Au. 2023 Aug 30;3(6):494-506. doi: 10.1021/acsbiomedchemau.3c00038. eCollection 2023 Dec 20. ACS Bio Med Chem Au. 2023. PMID: 38144255 Free PMC article.
Rational design, synthesis, molecular modeling, biological activity, and mechanism of action of polypharmacological norfloxacin hydroxamic acid derivatives.
Kamal El-Sagheir AM, Abdelmesseh Nekhala I, Abd El-Gaber MK, Aboraia AS, Persson J, Schäfer AB, Wenzel M, Omar FA. Kamal El-Sagheir AM, et al. Among authors: schafer ab. RSC Med Chem. 2023 Sep 19;14(12):2593-2610. doi: 10.1039/d3md00309d. eCollection 2023 Dec 13. RSC Med Chem. 2023. PMID: 38099058 Free PMC article.
Dual Action of Eeyarestatin 24 on Sec-Dependent Protein Secretion and Bacterial DNA.
Schäfer AB, Steenhuis M, Jim KK, Neef J, O'Keefe S, Whitehead RC, Swanton E, Wang B, Halbedel S, High S, van Dijl JM, Luirink J, Wenzel M. Schäfer AB, et al. ACS Infect Dis. 2023 Feb 10;9(2):253-269. doi: 10.1021/acsinfecdis.2c00404. Epub 2023 Jan 13. ACS Infect Dis. 2023. PMID: 36637435 Free PMC article.
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