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A Reactive Antibody Platform for One-Step Production of Antibody-Drug Conjugates through a Diels-Alder Reaction with Maleimide.
St Amant AH, Huang F, Lin J, Lemen D, Chakiath C, Mao S, Fazenbaker C, Zhong H, Harper J, Xu W, Patel N, Adams L, Vijayakrishnan B, Howard PW, Marelli M, Wu H, Gao C, Read de Alaniz J, Christie RJ. St Amant AH, et al. Among authors: patel n. Bioconjug Chem. 2019 Sep 18;30(9):2340-2348. doi: 10.1021/acs.bioconjchem.9b00436. Epub 2019 Aug 19. Bioconjug Chem. 2019. PMID: 31380623
Potentiation of PBD Dimers by Lipophilicity Manipulation.
Cailleau T, Adams LR, Arora N, Kang GD, Masterson L, Patel N, Hartley JA, Mao S, Harper J, Howard PW. Cailleau T, et al. Among authors: patel n. Curr Top Med Chem. 2019;19(9):741-752. doi: 10.2174/1568026619666190401112517. Curr Top Med Chem. 2019. PMID: 30931859
Efficacy, Tolerability, and Pharmacokinetic Studies of Antibody-Drug Conjugates Containing a Low-Potency Pyrrolobenzodiazepine Dimer.
Gregson SJ, Pugh K, Patel N, Afif-Rider S, Vijayakrishnan B, Santos K, Riedl J, Hutchinson I, Kang GD, Chooi KP, Beard R, Adams L, Barry CS, Ball K, Masterson LA, McFarlane M, Hartley JA, Howard PW. Gregson SJ, et al. Among authors: patel n. Mol Cancer Ther. 2022 Sep 6;21(9):1439-1448. doi: 10.1158/1535-7163.MCT-22-0145. Mol Cancer Ther. 2022. PMID: 35793464
Fractionated Dosing Improves Preclinical Therapeutic Index of Pyrrolobenzodiazepine-Containing Antibody Drug Conjugates.
Hinrichs MJM, Ryan PM, Zheng B, Afif-Rider S, Yu XQ, Gunsior M, Zhong H, Harper J, Bezabeh B, Vashisht K, Rebelatto M, Reed M, Ryan PC, Breen S, Patel N, Chen C, Masterson L, Tiberghien A, Howard PW, Dimasi N, Dixit R. Hinrichs MJM, et al. Among authors: patel n. Clin Cancer Res. 2017 Oct 1;23(19):5858-5868. doi: 10.1158/1078-0432.CCR-17-0219. Epub 2017 Jun 19. Clin Cancer Res. 2017. PMID: 28630216
TR1801-ADC: a highly potent cMet antibody-drug conjugate with high activity in patient-derived xenograft models of solid tumors.
Gymnopoulos M, Betancourt O, Blot V, Fujita R, Galvan D, Lieuw V, Nguyen S, Snedden J, Stewart C, Villicana J, Wojciak J, Wong E, Pardo R, Patel N, D'Hooge F, Vijayakrishnan B, Barry C, Hartley JA, Howard PW, Newman R, Coronella J. Gymnopoulos M, et al. Among authors: patel n. Mol Oncol. 2020 Jan;14(1):54-68. doi: 10.1002/1878-0261.12600. Epub 2019 Dec 3. Mol Oncol. 2020. PMID: 31736230 Free PMC article.
Phase 2 Trial of Veliparib, Local Irradiation and Temozolomide in Patients with Newly Diagnosed High-Grade Glioma: A Children's Oncology Group Study.
Karajannis MA, Onar-Thomas A, Lin T, Baxter PA, Boué DR, Cole BL, Fuller C, Haque S, Jabado N, Lucas JT Jr, MacDonald SM, Matsushima C, Patel N, Pierson CR, Souweidane MM, Thomas DL, Walsh MF, Zaky W, Leary SES, Gajjar A, Fouladi M, Cohen KJ. Karajannis MA, et al. Among authors: patel n. Neuro Oncol. 2024 Nov 19:noae247. doi: 10.1093/neuonc/noae247. Online ahead of print. Neuro Oncol. 2024. PMID: 39560182
AAAAI-EAACI PRACTALL: Standardizing oral food challenges-2024 Update.
Sampson HA, Arasi S, Bahnson HT, Ballmer-Weber B, Beyer K, Bindslev-Jensen C, Bird JA, Blumchen K, Davis C, Ebisawa M, Nowak-Wegrzyn A, Patel N, Peters RL, Sicherer S, Spergel J, Turner PJ, Yanagida N, Eigenmann PA. Sampson HA, et al. Among authors: patel n. Pediatr Allergy Immunol. 2024 Nov;35(11):e14276. doi: 10.1111/pai.14276. Pediatr Allergy Immunol. 2024. PMID: 39560049 Review.
9,621 results