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Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians.
Franceschi C, Olivieri F, Marchegiani F, Cardelli M, Cavallone L, Capri M, Salvioli S, Valensin S, De Benedictis G, Di Iorio A, Caruso C, Paolisso G, Monti D. Franceschi C, et al. Among authors: olivieri f. Mech Ageing Dev. 2005 Feb;126(2):351-61. doi: 10.1016/j.mad.2004.08.028. Mech Ageing Dev. 2005. PMID: 15621218 Review.
MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling.
Olivieri F, Lazzarini R, Recchioni R, Marcheselli F, Rippo MR, Di Nuzzo S, Albertini MC, Graciotti L, Babini L, Mariotti S, Spada G, Abbatecola AM, Antonicelli R, Franceschi C, Procopio AD. Olivieri F, et al. Age (Dordr). 2013 Aug;35(4):1157-72. doi: 10.1007/s11357-012-9440-8. Epub 2012 Jun 13. Age (Dordr). 2013. PMID: 22692818 Free PMC article.
Age-related differences in the expression of circulating microRNAs: miR-21 as a new circulating marker of inflammaging.
Olivieri F, Spazzafumo L, Santini G, Lazzarini R, Albertini MC, Rippo MR, Galeazzi R, Abbatecola AM, Marcheselli F, Monti D, Ostan R, Cevenini E, Antonicelli R, Franceschi C, Procopio AD. Olivieri F, et al. Mech Ageing Dev. 2012 Nov-Dec;133(11-12):675-85. doi: 10.1016/j.mad.2012.09.004. Epub 2012 Oct 2. Mech Ageing Dev. 2012. PMID: 23041385
Low FasL levels promote proliferation of human bone marrow-derived mesenchymal stem cells, higher levels inhibit their differentiation into adipocytes.
Rippo MR, Babini L, Prattichizzo F, Graciotti L, Fulgenzi G, Tomassoni Ardori F, Olivieri F, Borghetti G, Cinti S, Poloni A, Fazioli F, Procopio AD. Rippo MR, et al. Among authors: olivieri f. Cell Death Dis. 2013 Apr 18;4(4):e594. doi: 10.1038/cddis.2013.115. Cell Death Dis. 2013. PMID: 23598406 Free PMC article.
MicroRNAs linking inflamm-aging, cellular senescence and cancer.
Olivieri F, Rippo MR, Monsurrò V, Salvioli S, Capri M, Procopio AD, Franceschi C. Olivieri F, et al. Ageing Res Rev. 2013 Sep;12(4):1056-68. doi: 10.1016/j.arr.2013.05.001. Epub 2013 May 17. Ageing Res Rev. 2013. PMID: 23688930 Review.
Anti-inflammatory effect of ubiquinol-10 on young and senescent endothelial cells via miR-146a modulation.
Olivieri F, Lazzarini R, Babini L, Prattichizzo F, Rippo MR, Tiano L, Di Nuzzo S, Graciotti L, Festa R, Brugè F, Orlando P, Silvestri S, Capri M, Palma L, Magnani M, Franceschi C, Littarru GP, Procopio AD. Olivieri F, et al. Free Radic Biol Med. 2013 Oct;63:410-20. doi: 10.1016/j.freeradbiomed.2013.05.033. Epub 2013 May 30. Free Radic Biol Med. 2013. PMID: 23727324
359 results