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A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma-A Proof of Antigen Discovery Feasibility in Three Patients.
Bassani-Sternberg M, Digklia A, Huber F, Wagner D, Sempoux C, Stevenson BJ, Thierry AC, Michaux J, Pak H, Racle J, Boudousquie C, Balint K, Coukos G, Gfeller D, Martin Lluesma S, Harari A, Demartines N, Kandalaft LE. Bassani-Sternberg M, et al. Among authors: huber f. Front Immunol. 2019 Aug 8;10:1832. doi: 10.3389/fimmu.2019.01832. eCollection 2019. Front Immunol. 2019. PMID: 31440238 Free PMC article. Clinical Trial.
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes.
Chong C, Müller M, Pak H, Harnett D, Huber F, Grun D, Leleu M, Auger A, Arnaud M, Stevenson BJ, Michaux J, Bilic I, Hirsekorn A, Calviello L, Simó-Riudalbas L, Planet E, Lubiński J, Bryśkiewicz M, Wiznerowicz M, Xenarios I, Zhang L, Trono D, Harari A, Ohler U, Coukos G, Bassani-Sternberg M. Chong C, et al. Among authors: huber f. Nat Commun. 2020 Mar 10;11(1):1293. doi: 10.1038/s41467-020-14968-9. Nat Commun. 2020. PMID: 32157095 Free PMC article.
Rapid tumor vaccine using Toll-like receptor-activated ovarian cancer ascites monocytes.
Adams SF, Grimm AJ, Chiang CL, Mookerjee A, Flies D, Jean S, McCann GA, Michaux J, Pak H, Huber F, Neal C, Dangaj D, Bassani-Sternberg M, Rusakiewicz S, Facciabene A, Coukos G, Gimotty PA, Kandalaft LE. Adams SF, et al. Among authors: huber f. J Immunother Cancer. 2020 Aug;8(2):e000875. doi: 10.1136/jitc-2020-000875. J Immunother Cancer. 2020. PMID: 32817208 Free PMC article.
Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting.
Schmidt J, Smith AR, Magnin M, Racle J, Devlin JR, Bobisse S, Cesbron J, Bonnet V, Carmona SJ, Huber F, Ciriello G, Speiser DE, Bassani-Sternberg M, Coukos G, Baker BM, Harari A, Gfeller D. Schmidt J, et al. Among authors: huber f. Cell Rep Med. 2021 Feb 6;2(2):100194. doi: 10.1016/j.xcrm.2021.100194. eCollection 2021 Feb 16. Cell Rep Med. 2021. PMID: 33665637 Free PMC article.
Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer.
Tanyi JL, Chiang CL, Chiffelle J, Thierry AC, Baumgartener P, Huber F, Goepfert C, Tarussio D, Tissot S, Torigian DA, Nisenbaum HL, Stevenson BJ, Guiren HF, Ahmed R, Huguenin-Bergenat AL, Zsiros E, Bassani-Sternberg M, Mick R, Powell DJ Jr, Coukos G, Harari A, Kandalaft LE. Tanyi JL, et al. Among authors: huber f. NPJ Vaccines. 2021 Mar 15;6(1):36. doi: 10.1038/s41541-021-00297-5. NPJ Vaccines. 2021. PMID: 33723260 Free PMC article.
Author Correction: Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer.
Tanyi JL, Chiang CL, Chiffelle J, Thierry AC, Baumgartener P, Huber F, Goepfert C, Tarussio D, Tissot S, Torigian DA, Nisenbaum HL, Stevenson BJ, Guiren HF, Ahmed R, Huguenin-Bergenat AL, Zsiros E, Bassani-Sternberg M, Mick R, Powell DJ Jr, Coukos G, Harari A, Kandalaft LE. Tanyi JL, et al. Among authors: huber f. NPJ Vaccines. 2021 May 4;6(1):68. doi: 10.1038/s41541-021-00332-5. NPJ Vaccines. 2021. PMID: 33947868 Free PMC article. No abstract available.
Sensitive identification of neoantigens and cognate TCRs in human solid tumors.
Arnaud M, Chiffelle J, Genolet R, Navarro Rodrigo B, Perez MAS, Huber F, Magnin M, Nguyen-Ngoc T, Guillaume P, Baumgaertner P, Chong C, Stevenson BJ, Gfeller D, Irving M, Speiser DE, Schmidt J, Zoete V, Kandalaft LE, Bassani-Sternberg M, Bobisse S, Coukos G, Harari A. Arnaud M, et al. Among authors: huber f. Nat Biotechnol. 2022 May;40(5):656-660. doi: 10.1038/s41587-021-01072-6. Epub 2021 Nov 15. Nat Biotechnol. 2022. PMID: 34782741 Free PMC article.
A Personalized Neoantigen Vaccine in Combination with Platinum-Based Chemotherapy Induces a T-Cell Response Coinciding with a Complete Response in Endometrial Carcinoma.
Harari A, Sarivalasis A, de Jonge K, Thierry AC, Huber F, Boudousquie C, Rossier L, Orcurto A, Imbimbo M, Baumgaertner P, Bassani-Sternberg M, Kandalaft LE. Harari A, et al. Among authors: huber f. Cancers (Basel). 2021 Nov 18;13(22):5801. doi: 10.3390/cancers13225801. Cancers (Basel). 2021. PMID: 34830955 Free PMC article.
548 results