Holzbaur ELF - Search Results

1

The ADP/ATP translocase drives mitophagy independent of nucleotide exchange.

Hoshino A, Wang WJ, Wada S, McDermott-Roe C, Evans CS, Gosis B, Morley MP, Rathi KS, Li J, Li K, Yang S, McManus MJ, Bowman C, Potluri P, Levin M, Damrauer S, Wallace DC, Holzbaur ELF, Arany Z. Hoshino A, et al. Among authors: holzbaur elf. Nature. 2019 Nov;575(7782):375-379. doi: 10.1038/s41586-019-1667-4. Epub 2019 Oct 16. Nature. 2019. PMID: 31618756 Free PMC article.

2

Processive bidirectional motion of dynein-dynactin complexes in vitro.

Ross JL, Wallace K, Shuman H, Goldman YE, Holzbaur EL. Ross JL, et al. Nat Cell Biol. 2006 Jun;8(6):562-70. doi: 10.1038/ncb1421. Epub 2006 May 21. Nat Cell Biol. 2006. PMID: 16715075

3

Dynactin functions as both a dynamic tether and brake during dynein-driven motility.

Ayloo S, Lazarus JE, Dodda A, Tokito M, Ostap EM, Holzbaur EL. Ayloo S, et al. Nat Commun. 2014 Sep 4;5:4807. doi: 10.1038/ncomms5807. Nat Commun. 2014. PMID: 25185702 Free PMC article.

4

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.

Wong YC, Holzbaur EL. Wong YC, et al. Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4439-48. doi: 10.1073/pnas.1405752111. Epub 2014 Oct 7. Proc Natl Acad Sci U S A. 2014. PMID: 25294927 Free PMC article.

5

Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria.

Wong YC, Holzbaur EL. Wong YC, et al. Autophagy. 2015;11(2):422-4. doi: 10.1080/15548627.2015.1009792. Autophagy. 2015. PMID: 25801386 Free PMC article.

6

Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy.

Moore AS, Holzbaur EL. Moore AS, et al. Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):E3349-58. doi: 10.1073/pnas.1523810113. Epub 2016 May 31. Proc Natl Acad Sci U S A. 2016. PMID: 27247382 Free PMC article.

7

Spatiotemporal dynamics of autophagy receptors in selective mitophagy.

Moore AS, Holzbaur EL. Moore AS, et al. Autophagy. 2016 Oct 2;12(10):1956-1957. doi: 10.1080/15548627.2016.1212788. Epub 2016 Aug 2. Autophagy. 2016. PMID: 27484150 Free PMC article.

8

Autophagy and mitophagy in ALS.

Evans CS, Holzbaur ELF. Evans CS, et al. Among authors: holzbaur elf. Neurobiol Dis. 2019 Feb;122:35-40. doi: 10.1016/j.nbd.2018.07.005. Epub 2018 Jul 5. Neurobiol Dis. 2019. PMID: 29981842 Free PMC article. Review.

9

Quality Control in Neurons: Mitophagy and Other Selective Autophagy Mechanisms.

Evans CS, Holzbaur ELF. Evans CS, et al. Among authors: holzbaur elf. J Mol Biol. 2020 Jan 3;432(1):240-260. doi: 10.1016/j.jmb.2019.06.031. Epub 2019 Jul 8. J Mol Biol. 2020. PMID: 31295455 Free PMC article. Review.

10

Degradation of engulfed mitochondria is rate-limiting in Optineurin-mediated mitophagy in neurons.

Evans CS, Holzbaur EL. Evans CS, et al. Elife. 2020 Jan 14;9:e50260. doi: 10.7554/eLife.50260. Elife. 2020. PMID: 31934852 Free PMC article.

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