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The ADP/ATP translocase drives mitophagy independent of nucleotide exchange.
Hoshino A, Wang WJ, Wada S, McDermott-Roe C, Evans CS, Gosis B, Morley MP, Rathi KS, Li J, Li K, Yang S, McManus MJ, Bowman C, Potluri P, Levin M, Damrauer S, Wallace DC, Holzbaur ELF, Arany Z. Hoshino A, et al. Among authors: wang wj. Nature. 2019 Nov;575(7782):375-379. doi: 10.1038/s41586-019-1667-4. Epub 2019 Oct 16. Nature. 2019. PMID: 31618756 Free PMC article.
The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK.
Zhan YY, Chen Y, Zhang Q, Zhuang JJ, Tian M, Chen HZ, Zhang LR, Zhang HK, He JP, Wang WJ, Wu R, Wang Y, Shi C, Yang K, Li AZ, Xin YZ, Li TY, Yang JY, Zheng ZH, Yu CD, Lin SC, Chang C, Huang PQ, Lin T, Wu Q. Zhan YY, et al. Among authors: wang y, wang wj. Nat Chem Biol. 2012 Nov;8(11):897-904. doi: 10.1038/nchembio.1069. Epub 2012 Sep 16. Nat Chem Biol. 2012. PMID: 22983157
Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway.
Wang WJ, Wang Y, Chen HZ, Xing YZ, Li FW, Zhang Q, Zhou B, Zhang HK, Zhang J, Bian XL, Li L, Liu Y, Zhao BX, Chen Y, Wu R, Li AZ, Yao LM, Chen P, Zhang Y, Tian XY, Beermann F, Wu M, Han J, Huang PQ, Lin T, Wu Q. Wang WJ, et al. Among authors: wang y. Nat Chem Biol. 2014 Feb;10(2):133-40. doi: 10.1038/nchembio.1406. Epub 2013 Dec 8. Nat Chem Biol. 2014. PMID: 24316735
Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Li L, Liu Y, Chen HZ, Li FW, Wu JF, Zhang HK, He JP, Xing YZ, Chen Y, Wang WJ, Tian XY, Li AZ, Zhang Q, Huang PQ, Han J, Lin T, Wu Q. Li L, et al. Among authors: wang wj. Nat Chem Biol. 2015 May;11(5):339-46. doi: 10.1038/nchembio.1788. Epub 2015 Mar 30. Nat Chem Biol. 2015. PMID: 25822914 Free article.
2,106 results