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Integrative analysis of prognostic biomarkers derived from multiomics panels helps discrimination of chronic kidney disease trajectories in people with type 2 diabetes.
Kammer M, Heinzel A, Willency JA, Duffin KL, Mayer G, Simons K, Gerl MJ, Klose C, Heinze G, Reindl-Schwaighofer R, Hu K, Perco P, Eder S, Rosivall L, Mark PB, Ju W, Kretzler M, McCarthy MI, Heerspink HL, Wiecek A, Gomez MF, Oberbauer R; BEAt-DKD Consortium. Kammer M, et al. Among authors: duffin kl. Kidney Int. 2019 Dec;96(6):1381-1388. doi: 10.1016/j.kint.2019.07.025. Epub 2019 Aug 30. Kidney Int. 2019. PMID: 31679767 Free article.
Markers of early progressive renal decline in type 2 diabetes suggest different implications for etiological studies and prognostic tests development.
Nowak N, Skupien J, Smiles AM, Yamanouchi M, Niewczas MA, Galecki AT, Duffin KL, Breyer MD, Pullen N, Bonventre JV, Krolewski AS. Nowak N, et al. Among authors: duffin kl. Kidney Int. 2018 May;93(5):1198-1206. doi: 10.1016/j.kint.2017.11.024. Epub 2018 Feb 2. Kidney Int. 2018. PMID: 29398132 Free PMC article.
JAK1/JAK2 inhibition by baricitinib in diabetic kidney disease: results from a Phase 2 randomized controlled clinical trial.
Tuttle KR, Brosius FC 3rd, Adler SG, Kretzler M, Mehta RL, Tumlin JA, Tanaka Y, Haneda M, Liu J, Silk ME, Cardillo TE, Duffin KL, Haas JV, Macias WL, Nunes FP, Janes JM. Tuttle KR, et al. Among authors: duffin kl. Nephrol Dial Transplant. 2018 Nov 1;33(11):1950-1959. doi: 10.1093/ndt/gfx377. Nephrol Dial Transplant. 2018. PMID: 29481660 Free PMC article. Clinical Trial.
Validation of Plasma Biomarker Candidates for the Prediction of eGFR Decline in Patients With Type 2 Diabetes.
Heinzel A, Kammer M, Mayer G, Reindl-Schwaighofer R, Hu K, Perco P, Eder S, Rosivall L, Mark PB, Ju W, Kretzler M, Gilmour P, Wilson JM, Duffin KL, Abdalla M, McCarthy MI, Heinze G, Heerspink HL, Wiecek A, Gomez MF, Oberbauer R; BEAt-DKD Consortium. Heinzel A, et al. Among authors: duffin kl. Diabetes Care. 2018 Sep;41(9):1947-1954. doi: 10.2337/dc18-0532. Epub 2018 Jul 6. Diabetes Care. 2018. PMID: 29980527 Free PMC article.
A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes.
Niewczas MA, Pavkov ME, Skupien J, Smiles A, Md Dom ZI, Wilson JM, Park J, Nair V, Schlafly A, Saulnier PJ, Satake E, Simeone CA, Shah H, Qiu C, Looker HC, Fiorina P, Ware CF, Sun JK, Doria A, Kretzler M, Susztak K, Duffin KL, Nelson RG, Krolewski AS. Niewczas MA, et al. Among authors: duffin kl. Nat Med. 2019 May;25(5):805-813. doi: 10.1038/s41591-019-0415-5. Epub 2019 Apr 22. Nat Med. 2019. PMID: 31011203 Free PMC article.
Comprehensive Search for Novel Circulating miRNAs and Axon Guidance Pathway Proteins Associated with Risk of ESKD in Diabetes.
Satake E, Saulnier PJ, Kobayashi H, Gupta MK, Looker HC, Wilson JM, Md Dom ZI, Ihara K, O'Neil K, Krolewski B, Pipino C, Pavkov ME, Nair V, Bitzer M, Niewczas MA, Kretzler M, Mauer M, Doria A, Najafian B, Kulkarni RN, Duffin KL, Pezzolesi MG, Kahn CR, Nelson RG, Krolewski AS. Satake E, et al. Among authors: duffin kl. J Am Soc Nephrol. 2021 Sep;32(9):2331-2351. doi: 10.1681/ASN.2021010105. Epub 2021 Jun 17. J Am Soc Nephrol. 2021. PMID: 34140396 Free PMC article.
Circulating proteins protect against renal decline and progression to end-stage renal disease in patients with diabetes.
Md Dom ZI, Satake E, Skupien J, Krolewski B, O'Neil K, Willency JA, Dillon ST, Wilson JM, Kobayashi H, Ihara K, Libermann TA, Pragnell M, Duffin KL, Krolewski AS. Md Dom ZI, et al. Among authors: duffin kl. Sci Transl Med. 2021 Jun 30;13(600):eabd2699. doi: 10.1126/scitranslmed.abd2699. Sci Transl Med. 2021. PMID: 34193611 Free PMC article.
88 results