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Page 1
Identification of DHODH as a therapeutic target in small cell lung cancer.
Li L, Ng SR, Colón CI, Drapkin BJ, Hsu PP, Li Z, Nabel CS, Lewis CA, Romero R, Mercer KL, Bhutkar A, Phat S, Myers DT, Muzumdar MD, Westcott PMK, Beytagh MC, Farago AF, Vander Heiden MG, Dyson NJ, Jacks T. Li L, et al. Among authors: phat s. Sci Transl Med. 2019 Nov 6;11(517):eaaw7852. doi: 10.1126/scitranslmed.aaw7852. Sci Transl Med. 2019. PMID: 31694929 Free PMC article.
Combination Olaparib and Temozolomide in Relapsed Small-Cell Lung Cancer.
Farago AF, Yeap BY, Stanzione M, Hung YP, Heist RS, Marcoux JP, Zhong J, Rangachari D, Barbie DA, Phat S, Myers DT, Morris R, Kem M, Dubash TD, Kennedy EA, Digumarthy SR, Sequist LV, Hata AN, Maheswaran S, Haber DA, Lawrence MS, Shaw AT, Mino-Kenudson M, Dyson NJ, Drapkin BJ. Farago AF, et al. Among authors: phat s. Cancer Discov. 2019 Oct;9(10):1372-1387. doi: 10.1158/2159-8290.CD-19-0582. Epub 2019 Aug 15. Cancer Discov. 2019. PMID: 31416802 Free PMC article. Clinical Trial.
Genomic and Functional Fidelity of Small Cell Lung Cancer Patient-Derived Xenografts.
Drapkin BJ, George J, Christensen CL, Mino-Kenudson M, Dries R, Sundaresan T, Phat S, Myers DT, Zhong J, Igo P, Hazar-Rethinam MH, Licausi JA, Gomez-Caraballo M, Kem M, Jani KN, Azimi R, Abedpour N, Menon R, Lakis S, Heist RS, Büttner R, Haas S, Sequist LV, Shaw AT, Wong KK, Hata AN, Toner M, Maheswaran S, Haber DA, Peifer M, Dyson N, Thomas RK, Farago AF. Drapkin BJ, et al. Among authors: phat s. Cancer Discov. 2018 May;8(5):600-615. doi: 10.1158/2159-8290.CD-17-0935. Epub 2018 Feb 26. Cancer Discov. 2018. PMID: 29483136 Free PMC article.
Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish.
Yan C, Brunson DC, Tang Q, Do D, Iftimia NA, Moore JC, Hayes MN, Welker AM, Garcia EG, Dubash TD, Hong X, Drapkin BJ, Myers DT, Phat S, Volorio A, Marvin DL, Ligorio M, Dershowitz L, McCarthy KM, Karabacak MN, Fletcher JA, Sgroi DC, Iafrate JA, Maheswaran S, Dyson NJ, Haber DA, Rawls JF, Langenau DM. Yan C, et al. Among authors: phat s. Cell. 2019 Jun 13;177(7):1903-1914.e14. doi: 10.1016/j.cell.2019.04.004. Epub 2019 Apr 25. Cell. 2019. PMID: 31031007 Free PMC article.
Acquired Cross-Resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC Paralogs.
Pal Choudhuri S, Girard L, Lim JYS, Wise JF, Freitas B, Yang D, Wong E, Hamilton S, Chien VD, Kim YJ, Gilbreath C, Zhong J, Phat S, Myers DT, Christensen CL, Mazloom-Farsibaf H, Stanzione M, Wong KK, Hung YP, Farago AF, Meador CB, Dyson NJ, Lawrence MS, Wu S, Drapkin BJ. Pal Choudhuri S, et al. Among authors: phat s. Cancer Discov. 2024 May 1;14(5):804-827. doi: 10.1158/2159-8290.CD-23-0656. Cancer Discov. 2024. PMID: 38386926 Free PMC article.
Acquired Cross-resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC paralogs.
Choudhuri SP, Girard L, Lim JYS, Wise JF, Freitas B, Yang D, Wong E, Hamilton S, Chien VD, Gilbreath C, Zhong J, Phat S, Myers DT, Christensen CL, Stanzione M, Wong KK, Farago AF, Meador CB, Dyson NJ, Lawrence MS, Wu S, Drapkin BJ. Choudhuri SP, et al. Among authors: phat s. bioRxiv [Preprint]. 2023 Jun 28:2023.06.23.546278. doi: 10.1101/2023.06.23.546278. bioRxiv. 2023. Update in: Cancer Discov. 2024 May 1;14(5):804-827. doi: 10.1158/2159-8290.CD-23-0656. PMID: 37425738 Free PMC article. Updated. Preprint.
Natural cytotoxicity receptor-dependent natural killer cytolytic activity directed at hepatitis C Virus (HCV) is associated with liver inflammation, African American race, IL28B genotype, and response to pegylated interferon/ribavirin therapy in chronic HCV infection.
Meng Q, Rani MR, Sugalski JM, Judge CJ, Phat S, Rodriguez B, Blanton RE, Anthony DD. Meng Q, et al. Among authors: phat s. J Infect Dis. 2014 May 15;209(10):1591-601. doi: 10.1093/infdis/jit677. Epub 2013 Dec 2. J Infect Dis. 2014. PMID: 24302757 Free PMC article.