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Page 1
Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling.
Valencia AM, Collings CK, Dao HT, St Pierre R, Cheng YC, Huang J, Sun ZY, Seo HS, Mashtalir N, Comstock DE, Bolonduro O, Vangos NE, Yeoh ZC, Dornon MK, Hermawan C, Barrett L, Dhe-Paganon S, Woolf CJ, Muir TW, Kadoch C. Valencia AM, et al. Among authors: mashtalir n. Cell. 2019 Nov 27;179(6):1342-1356.e23. doi: 10.1016/j.cell.2019.10.044. Epub 2019 Nov 20. Cell. 2019. PMID: 31759698 Free PMC article.
The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma.
McBride MJ, Mashtalir N, Winter EB, Dao HT, Filipovski M, D'Avino AR, Seo HS, Umbreit NT, St Pierre R, Valencia AM, Qian K, Zullow HJ, Jaffe JD, Dhe-Paganon S, Muir TW, Kadoch C. McBride MJ, et al. Among authors: mashtalir n. Nat Struct Mol Biol. 2020 Sep;27(9):836-845. doi: 10.1038/s41594-020-0466-9. Epub 2020 Aug 3. Nat Struct Mol Biol. 2020. PMID: 32747783 Free PMC article.
SMARCE1 deficiency generates a targetable mSWI/SNF dependency in clear cell meningioma.
St Pierre R, Collings CK, Samé Guerra DD, Widmer CJ, Bolonduro O, Mashtalir N, Sankar A, Liang Y, Bi WL, Gerkes EH, Ramesh V, Qi J, Smith MJ, Meredith DM, Kadoch C. St Pierre R, et al. Among authors: mashtalir n. Nat Genet. 2022 Jun;54(6):861-873. doi: 10.1038/s41588-022-01077-0. Epub 2022 Jun 9. Nat Genet. 2022. PMID: 35681054
Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes.
Mashtalir N, D'Avino AR, Michel BC, Luo J, Pan J, Otto JE, Zullow HJ, McKenzie ZM, Kubiak RL, St Pierre R, Valencia AM, Poynter SJ, Cassel SH, Ranish JA, Kadoch C. Mashtalir N, et al. Cell. 2018 Nov 15;175(5):1272-1288.e20. doi: 10.1016/j.cell.2018.09.032. Epub 2018 Oct 18. Cell. 2018. PMID: 30343899 Free PMC article.
A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.
Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM, Pan J, Remillard DI, Lareau CA, Zullow HJ, Fortoul N, Gray NS, Bradner JE, Chan HM, Kadoch C. Michel BC, et al. Among authors: mashtalir n. Nat Cell Biol. 2018 Dec;20(12):1410-1420. doi: 10.1038/s41556-018-0221-1. Epub 2018 Nov 5. Nat Cell Biol. 2018. PMID: 30397315 Free PMC article.
A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms.
Mashtalir N, Suzuki H, Farrell DP, Sankar A, Luo J, Filipovski M, D'Avino AR, St Pierre R, Valencia AM, Onikubo T, Roeder RG, Han Y, He Y, Ranish JA, DiMaio F, Walz T, Kadoch C. Mashtalir N, et al. Cell. 2020 Oct 29;183(3):802-817.e24. doi: 10.1016/j.cell.2020.09.051. Epub 2020 Oct 13. Cell. 2020. PMID: 33053319 Free PMC article.
Author Correction: The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma.
McBride MJ, Mashtalir N, Winter EB, Dao HT, Filipovski M, D'Avino AR, Seo HS, Umbreit NT, St Pierre R, Valencia AM, Qian K, Zullow HJ, Jaffe JD, Dhe-Paganon S, Muir TW, Kadoch C. McBride MJ, et al. Among authors: mashtalir n. Nat Struct Mol Biol. 2021 Jan;28(1):118. doi: 10.1038/s41594-020-00540-y. Nat Struct Mol Biol. 2021. PMID: 33273722 Free PMC article. No abstract available.
34 results