Liu S - Search Results

1

CDK5RAP3 is a co-factor for the oncogenic transcription factor STAT3.

Egusquiaguirre SP, Liu S, Tošić I, Jiang K, Walker SR, Nicolais M, Saw TY, Xiang M, Bartel K, Nelson EA, Frank DA. Egusquiaguirre SP, et al. Among authors: liu s. Neoplasia. 2020 Jan;22(1):47-59. doi: 10.1016/j.neo.2019.10.002. Epub 2019 Nov 22. Neoplasia. 2020. PMID: 31765941 Free PMC article.

2

STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-κB to IL-6 signaling axis and STAT3-driven cancer phenotypes.

Xiang M, Birkbak NJ, Vafaizadeh V, Walker SR, Yeh JE, Liu S, Kroll Y, Boldin M, Taganov K, Groner B, Richardson AL, Frank DA. Xiang M, et al. Among authors: liu s. Sci Signal. 2014 Jan 28;7(310):ra11. doi: 10.1126/scisignal.2004497. Sci Signal. 2014. PMID: 24473196 Free PMC article.

3

The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells.

Egusquiaguirre SP, Yeh JE, Walker SR, Liu S, Frank DA. Egusquiaguirre SP, et al. Among authors: liu s. Neoplasia. 2018 May;20(5):489-498. doi: 10.1016/j.neo.2018.03.004. Epub 2018 Apr 2. Neoplasia. 2018. PMID: 29621649 Free PMC article.

4

Targeting STAT5 in hematologic malignancies through inhibition of the bromodomain and extra-terminal (BET) bromodomain protein BRD2.

Liu S, Walker SR, Nelson EA, Cerulli R, Xiang M, Toniolo PA, Qi J, Stone RM, Wadleigh M, Bradner JE, Frank DA. Liu S, et al. Mol Cancer Ther. 2014 May;13(5):1194-205. doi: 10.1158/1535-7163.MCT-13-0341. Epub 2014 Jan 16. Mol Cancer Ther. 2014. PMID: 24435449 Free PMC article.

5

Inhibiting STAT5 by the BET bromodomain inhibitor JQ1 disrupts human dendritic cell maturation.

Toniolo PA, Liu S, Yeh JE, Moraes-Vieira PM, Walker SR, Vafaizadeh V, Barbuto JA, Frank DA. Toniolo PA, et al. Among authors: liu s. J Immunol. 2015 Apr 1;194(7):3180-90. doi: 10.4049/jimmunol.1401635. Epub 2015 Feb 27. J Immunol. 2015. PMID: 25725100 Free PMC article.

6

Deregulation of SOCS5 suppresses dendritic cell function in chronic lymphocytic leukemia.

Toniolo PA, Liu S, Yeh JE, Ye DQ, Barbuto JA, Frank DA. Toniolo PA, et al. Among authors: liu s. Oncotarget. 2016 Jul 19;7(29):46301-46314. doi: 10.18632/oncotarget.10093. Oncotarget. 2016. PMID: 27317770 Free PMC article.

7

Gene expression-based discovery of atovaquone as a STAT3 inhibitor and anticancer agent.

Xiang M, Kim H, Ho VT, Walker SR, Bar-Natan M, Anahtar M, Liu S, Toniolo PA, Kroll Y, Jones N, Giaccone ZT, Heppler LN, Ye DQ, Marineau JJ, Shaw D, Bradner JE, Blonquist T, Neuberg D, Hetz C, Stone RM, Soiffer RJ, Frank DA. Xiang M, et al. Among authors: liu s. Blood. 2016 Oct 6;128(14):1845-1853. doi: 10.1182/blood-2015-07-660506. Epub 2016 Aug 16. Blood. 2016. PMID: 27531676 Free PMC article.

8

The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy.

Liu S, Marneth AE, Alexe G, Walker SR, Gandler HI, Ye DQ, Labella K, Mathur R, Toniolo PA, Tillgren M, Gokhale PC, Barbie D, Mullally A, Stegmaier K, Frank DA. Liu S, et al. Blood Adv. 2018 Dec 11;2(23):3428-3442. doi: 10.1182/bloodadvances.2018016733. Blood Adv. 2018. PMID: 30504235 Free PMC article.

9

Mutant KRAS Downregulates the Receptor for Leukemia Inhibitory Factor (LIF) to Enhance a Signature of Glycolysis in Pancreatic Cancer and Lung Cancer.

Liu S, Gandler HI, Tošić I, Ye DQ, Giaccone ZT, Frank DA. Liu S, et al. Mol Cancer Res. 2021 Aug;19(8):1283-1295. doi: 10.1158/1541-7786.MCR-20-0633. Epub 2021 Apr 30. Mol Cancer Res. 2021. PMID: 33931487 Free PMC article.

10

The transcriptional modulator BCL6 as a molecular target for breast cancer therapy.

Walker SR, Liu S, Xiang M, Nicolais M, Hatzi K, Giannopoulou E, Elemento O, Cerchietti L, Melnick A, Frank DA. Walker SR, et al. Among authors: liu s. Oncogene. 2015 Feb 26;34(9):1073-82. doi: 10.1038/onc.2014.61. Epub 2014 Mar 24. Oncogene. 2015. PMID: 24662818 Free PMC article.

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