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Page 1
Targeting JAK2 reduces GVHD and xenograft rejection through regulation of T cell differentiation.
Betts BC, Bastian D, Iamsawat S, Nguyen H, Heinrichs JL, Wu Y, Daenthanasanmak A, Veerapathran A, O'Mahony A, Walton K, Reff J, Horna P, Sagatys EM, Lee MC, Singer J, Chang YJ, Liu C, Pidala J, Anasetti C, Yu XZ. Betts BC, et al. Among authors: daenthanasanmak a. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1582-1587. doi: 10.1073/pnas.1712452115. Epub 2018 Jan 30. Proc Natl Acad Sci U S A. 2018. PMID: 29382747 Free PMC article.
Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells.
Nguyen H, Kuril S, Bastian D, Kim J, Zhang M, Vaena SG, Dany M, Dai M, Heinrichs JL, Daenthanasanmak A, Iamsawat S, Schutt S, Fu J, Wu Y, Fairlie DP, Atkinson C, Ogretmen B, Tomlinson S, Yu XZ. Nguyen H, et al. Among authors: daenthanasanmak a. JCI Insight. 2018 Dec 20;3(24):e121697. doi: 10.1172/jci.insight.121697. JCI Insight. 2018. PMID: 30568037 Free PMC article.
Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease.
Sofi MH, Wu Y, Schutt SD, Dai M, Daenthanasanmak A, Heinrichs Voss J, Nguyen H, Bastian D, Iamsawat S, Selvam SP, Liu C, Maulik N, Ogretmen B, Jin J, Mehrotra S, Yu XZ. Sofi MH, et al. Among authors: daenthanasanmak a. J Clin Invest. 2019 May 2;129(7):2760-2774. doi: 10.1172/JCI122899. J Clin Invest. 2019. PMID: 31045571 Free PMC article.
Targeting the Complement Alternative Pathway Permits Graft Versus Leukemia Activity while Preventing Graft Versus Host Disease.
Nguyen H, Alawieh A, Bastian D, Kuril S, Dai M, Daenthanasanmak A, Zhang M, Iamsawat S, Schutt SD, Wu Y, Sleiman MM, Shetty A, Atkinson C, Sun S, Varela JC, Tomlinson S, Yu XZ. Nguyen H, et al. Among authors: daenthanasanmak a. Clin Cancer Res. 2020 Jul 1;26(13):3481-3490. doi: 10.1158/1078-0432.CCR-19-1717. Epub 2020 Jan 9. Clin Cancer Res. 2020. PMID: 31919135 Free PMC article.
Ceramide synthesis regulates T cell activity and GVHD development.
Sofi MH, Heinrichs J, Dany M, Nguyen H, Dai M, Bastian D, Schutt S, Wu Y, Daenthanasanmak A, Gencer S, Zivkovic A, Szulc Z, Stark H, Liu C, Chang YJ, Ogretmen B, Yu XZ. Sofi MH, et al. Among authors: daenthanasanmak a. JCI Insight. 2017 May 18;2(10):e91701. doi: 10.1172/jci.insight.91701. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515365 Free PMC article.
25 results