Park JS - Search Results

1

SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity.

Lee DH, Park JS, Lee YS, Han J, Lee DK, Kwon SW, Han DH, Lee YH, Bae SH. Lee DH, et al. Among authors: park js. Autophagy. 2020 Nov;16(11):1949-1973. doi: 10.1080/15548627.2020.1712108. Epub 2020 Jan 10. Autophagy. 2020. PMID: 31913745 Free PMC article.

2

p62 prevents carbonyl cyanide m-chlorophenyl hydrazine (CCCP)-induced apoptotic cell death by activating Nrf2.

Park JS, Kang DH, Bae SH. Park JS, et al. Biochem Biophys Res Commun. 2015 Sep 4;464(4):1139-1144. doi: 10.1016/j.bbrc.2015.07.093. Epub 2015 Jul 22. Biochem Biophys Res Commun. 2015. PMID: 26208452

3

Fenofibrate activates Nrf2 through p62-dependent Keap1 degradation.

Park JS, Kang DH, Lee DH, Bae SH. Park JS, et al. Biochem Biophys Res Commun. 2015 Sep 25;465(3):542-7. doi: 10.1016/j.bbrc.2015.08.056. Epub 2015 Aug 14. Biochem Biophys Res Commun. 2015. PMID: 26282199

4

Concerted action of p62 and Nrf2 protects cells from palmitic acid-induced lipotoxicity.

Park JS, Kang DH, Lee DH, Bae SH. Park JS, et al. Biochem Biophys Res Commun. 2015 Oct 9;466(1):131-7. doi: 10.1016/j.bbrc.2015.08.120. Epub 2015 Aug 30. Biochem Biophys Res Commun. 2015. PMID: 26325428

5

PF-4708671, a specific inhibitor of p70 ribosomal S6 kinase 1, activates Nrf2 by promoting p62-dependent autophagic degradation of Keap1.

Park JS, Kang DH, Lee DH, Bae SH. Park JS, et al. Biochem Biophys Res Commun. 2015 Oct 23;466(3):499-504. doi: 10.1016/j.bbrc.2015.09.059. Epub 2015 Sep 14. Biochem Biophys Res Commun. 2015. PMID: 26381178

6

Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis.

Lee DH, Han DH, Nam KT, Park JS, Kim SH, Lee M, Kim G, Min BS, Cha BS, Lee YS, Sung SH, Jeong H, Ji HW, Lee MJ, Lee JS, Lee HY, Chun Y, Kim J, Komatsu M, Lee YH, Bae SH. Lee DH, et al. Among authors: park js. Free Radic Biol Med. 2016 Oct;99:520-532. doi: 10.1016/j.freeradbiomed.2016.09.009. Epub 2016 Sep 12. Free Radic Biol Med. 2016. PMID: 27634173

7

p62/SQSTM1 is required for the protection against endoplasmic reticulum stress-induced apoptotic cell death.

Park JS, Oh SY, Lee DH, Lee YS, Sung SH, Ji HW, Lee MJ, Lee YH, Rhee SG, Bae SH. Park JS, et al. Free Radic Res. 2016 Dec;50(12):1408-1421. doi: 10.1080/10715762.2016.1253073. Epub 2016 Nov 23. Free Radic Res. 2016. PMID: 27780373

8

The hypertension drug, verapamil, activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity.

Lee DH, Park JS, Lee YS, Sung SH, Lee YH, Bae SH. Lee DH, et al. Among authors: park js. BMB Rep. 2017 Feb;50(2):91-96. doi: 10.5483/bmbrep.2017.50.2.188. BMB Rep. 2017. PMID: 27998394 Free PMC article.

9

Inactivation of Sirtuin2 protects mice from acetaminophen-induced liver injury: possible involvement of ER stress and S6K1 activation.

Lee DH, Lee B, Park JS, Lee YS, Kim JH, Cho Y, Jo Y, Kim HS, Lee YH, Nam KT, Bae SH. Lee DH, et al. Among authors: park js. BMB Rep. 2019 Mar;52(3):190-195. doi: 10.5483/BMBRep.2019.52.3.083. BMB Rep. 2019. PMID: 30021675 Free PMC article.

10

The Antidiabetic Drug Lobeglitazone Protects Mice From Lipogenesis-Induced Liver Injury via Mechanistic Target of Rapamycin Complex 1 Inhibition.

Lee YS, Park JS, Lee DH, Lee DK, Kwon SW, Lee BW, Bae SH. Lee YS, et al. Among authors: park js. Front Endocrinol (Lausanne). 2018 Sep 21;9:539. doi: 10.3389/fendo.2018.00539. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 30298052 Free PMC article.

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