Lu S - Search Results

1

IL-1 Transcriptional Responses to Lipopolysaccharides Are Regulated by a Complex of RNA Binding Proteins.

Shi L, Song L, Maurer K, Dou Y, Patel VR, Su C, Leonard ME, Lu S, Hodge KM, Torres A, Chesi A, Grant SFA, Wells AD, Zhang Z, Petri MA, Sullivan KE. Shi L, et al. Among authors: lu s. J Immunol. 2020 Mar 1;204(5):1334-1344. doi: 10.4049/jimmunol.1900650. Epub 2020 Jan 17. J Immunol. 2020. PMID: 31953354 Free PMC article.

2

The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5.

Xia Q, Chesi A, Manduchi E, Johnston BT, Lu S, Leonard ME, Parlin UW, Rappaport EF, Huang P, Wells AD, Blobel GA, Johnson ME, Grant SFA. Xia Q, et al. Among authors: lu s. Diabetologia. 2016 Nov;59(11):2360-2368. doi: 10.1007/s00125-016-4077-2. Epub 2016 Aug 18. Diabetologia. 2016. PMID: 27539148

3

PARP-1 Inhibition Rescues Short Lifespan in Hyperglycemic C. Elegans And Improves GLP-1 Secretion in Human Cells.

Xia Q, Lu S, Ostrovsky J, McCormack SE, Falk MJ, Grant SFA. Xia Q, et al. Among authors: lu s. Aging Dis. 2018 Feb 1;9(1):17-30. doi: 10.14336/AD.2017.0230. eCollection 2018 Feb. Aging Dis. 2018. PMID: 29392078 Free PMC article.

4

Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density.

Chesi A, Wagley Y, Johnson ME, Manduchi E, Su C, Lu S, Leonard ME, Hodge KM, Pippin JA, Hankenson KD, Wells AD, Grant SFA. Chesi A, et al. Among authors: lu s. Nat Commun. 2019 Mar 19;10(1):1260. doi: 10.1038/s41467-019-09302-x. Nat Commun. 2019. PMID: 30890710 Free PMC article.

5

Canonical Notch signaling is required for bone morphogenetic protein-mediated human osteoblast differentiation.

Wagley Y, Chesi A, Acevedo PK, Lu S, Wells AD, Johnson ME, Grant SFA, Hankenson KD. Wagley Y, et al. Among authors: lu s. Stem Cells. 2020 Oct 1;38(10):1332-1347. doi: 10.1002/stem.3245. Epub 2020 Jun 24. Stem Cells. 2020. PMID: 32535942 Free article.

6

Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells.

Su C, Johnson ME, Torres A, Thomas RM, Manduchi E, Sharma P, Mehra P, Le Coz C, Leonard ME, Lu S, Hodge KM, Chesi A, Pippin J, Romberg N, Grant SFA, Wells AD. Su C, et al. Among authors: lu s. Nat Commun. 2020 Jul 3;11(1):3294. doi: 10.1038/s41467-020-17089-5. Nat Commun. 2020. PMID: 32620744 Free PMC article.

7

Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel Disease.

Lasconi C, Pahl MC, Cousminer DL, Doege CA, Chesi A, Hodge KM, Leonard ME, Lu S, Johnson ME, Su C, Hammond RK, Pippin JA, Terry NA, Ghanem LR, Leibel RL, Wells AD, Grant SFA. Lasconi C, et al. Among authors: lu s. Cell Mol Gastroenterol Hepatol. 2021;11(3):667-682. doi: 10.1016/j.jcmgh.2020.10.004. Epub 2020 Oct 16. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33069917 Free PMC article.

8

Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual.

Cousminer DL, Wagley Y, Pippin JA, Elhakeem A, Way GP, Pahl MC, McCormack SE, Chesi A, Mitchell JA, Kindler JM, Baird D, Hartley A, Howe L, Kalkwarf HJ, Lappe JM, Lu S, Leonard ME, Johnson ME, Hakonarson H, Gilsanz V, Shepherd JA, Oberfield SE, Greene CS, Kelly A, Lawlor DA, Voight BF, Wells AD, Zemel BS, Hankenson KD, Grant SFA. Cousminer DL, et al. Among authors: lu s. Genome Biol. 2021 Jan 4;22(1):1. doi: 10.1186/s13059-020-02207-9. Genome Biol. 2021. PMID: 33397451 Free PMC article.

9

Biological constraints on GWAS SNPs at suggestive significance thresholds reveal additional BMI loci.

Hammond RK, Pahl MC, Su C, Cousminer DL, Leonard ME, Lu S, Doege CA, Wagley Y, Hodge KM, Lasconi C, Johnson ME, Pippin JA, Hankenson KD, Leibel RL, Chesi A, Wells AD, Grant SF. Hammond RK, et al. Among authors: lu s. Elife. 2021 Jan 18;10:e62206. doi: 10.7554/eLife.62206. Elife. 2021. PMID: 33459256 Free PMC article.

10

3D promoter architecture re-organization during iPSC-derived neuronal cell differentiation implicates target genes for neurodevelopmental disorders.

Su C, Argenziano M, Lu S, Pippin JA, Pahl MC, Leonard ME, Cousminer DL, Johnson ME, Lasconi C, Wells AD, Chesi A, Grant SFA. Su C, et al. Among authors: lu s. Prog Neurobiol. 2021 Jun;201:102000. doi: 10.1016/j.pneurobio.2021.102000. Epub 2021 Feb 2. Prog Neurobiol. 2021. PMID: 33545232 Free PMC article.

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