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Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling.
Heitzler D, Durand G, Gallay N, Rizk A, Ahn S, Kim J, Violin JD, Dupuy L, Gauthier C, Piketty V, Crépieux P, Poupon A, Clément F, Fages F, Lefkowitz RJ, Reiter E. Heitzler D, et al. Among authors: poupon a. Mol Syst Biol. 2012 Jun 26;8:590. doi: 10.1038/msb.2012.22. Mol Syst Biol. 2012. PMID: 22735336 Free PMC article.
β-arrestin signalling and bias in hormone-responsive GPCRs.
Reiter E, Ayoub MA, Pellissier LP, Landomiel F, Musnier A, Tréfier A, Gandia J, De Pascali F, Tahir S, Yvinec R, Bruneau G, Poupon A, Crépieux P. Reiter E, et al. Among authors: poupon a. Mol Cell Endocrinol. 2017 Jul 5;449:28-41. doi: 10.1016/j.mce.2017.01.052. Epub 2017 Feb 4. Mol Cell Endocrinol. 2017. PMID: 28174117 Review.
G protein-dependent signaling triggers a β-arrestin-scaffolded p70S6K/ rpS6 module that controls 5'TOP mRNA translation.
Tréfier A, Musnier A, Landomiel F, Bourquard T, Boulo T, Ayoub MA, León K, Bruneau G, Chevalier M, Durand G, Blache MC, Inoue A, Fontaine J, Gauthier C, Tesseraud S, Reiter E, Poupon A, Crépieux P. Tréfier A, et al. Among authors: poupon a. FASEB J. 2018 Mar;32(3):1154-1169. doi: 10.1096/fj.201700763R. Epub 2018 Jan 3. FASEB J. 2018. PMID: 29084767
In addition, this study provides insights into how GPCR can exert trophic effects in the cell.-Trefier, A., Musnier, A., Landomiel, F., Bourquard, T., Boulo, T., Ayoub, M. A., Leon, K., Bruneau, G., Chevalier, M., Durand, G., Blache, M.-C., Inoue, A., …
In addition, this study provides insights into how GPCR can exert trophic effects in the cell.-Trefier, A., Musnier, A., Lando …
Biased Signaling and Allosteric Modulation at the FSHR.
Landomiel F, De Pascali F, Raynaud P, Jean-Alphonse F, Yvinec R, Pellissier LP, Bozon V, Bruneau G, Crépieux P, Poupon A, Reiter E. Landomiel F, et al. Among authors: poupon a. Front Endocrinol (Lausanne). 2019 Mar 13;10:148. doi: 10.3389/fendo.2019.00148. eCollection 2019. Front Endocrinol (Lausanne). 2019. PMID: 30930853 Free PMC article. Review.
Accurate determination of epitope for antibodies with unknown 3D structures.
Tahir S, Bourquard T, Musnier A, Jullian Y, Corde Y, Omahdi Z, Mathias L, Reiter E, Crépieux P, Bruneau G, Poupon A. Tahir S, et al. Among authors: poupon a. MAbs. 2021 Jan-Dec;13(1):1961349. doi: 10.1080/19420862.2021.1961349. MAbs. 2021. PMID: 34432559 Free PMC article.
Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor.
De Pascali F, Ayoub MA, Benevelli R, Sposini S, Lehoux J, Gallay N, Raynaud P, Landomiel F, Jean-Alphonse F, Gauthier C, Pellissier LP, Crépieux P, Poupon A, Inoue A, Joubert N, Viaud-Massuard MC, Casarini L, Simoni M, Hanyaloglu AC, Nataraja SG, Yu HN, Palmer SS, Yvinec R, Reiter E. De Pascali F, et al. Among authors: poupon a. Int J Mol Sci. 2021 Sep 12;22(18):9850. doi: 10.3390/ijms22189850. Int J Mol Sci. 2021. PMID: 34576014 Free PMC article.
A New in Silico Antibody Similarity Measure Both Identifies Large Sets of Epitope Binders with Distinct CDRs and Accurately Predicts Off-Target Reactivity.
Musnier A, Bourquard T, Vallet A, Mathias L, Bruneau G, Ayoub MA, Travert O, Corde Y, Gallay N, Boulo T, Cortes S, Watier H, Crépieux P, Reiter E, Poupon A. Musnier A, et al. Among authors: poupon a. Int J Mol Sci. 2022 Aug 28;23(17):9765. doi: 10.3390/ijms23179765. Int J Mol Sci. 2022. PMID: 36077163 Free PMC article.
83 results