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Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity.
Vialetto E, Miele S, Goren MG, Yu J, Yu Y, Collias D, Beamud B, Osbelt L, Lourenço M, Strowig T, Brisse S, Barquist L, Qimron U, Bikard D, Beisel CL. Vialetto E, et al. Nucleic Acids Res. 2024 Jun 10;52(10):6079-6091. doi: 10.1093/nar/gkae281. Nucleic Acids Res. 2024. PMID: 38661215 Free PMC article.
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA.
Dmytrenko O, Neumann GC, Hallmark T, Keiser DJ, Crowley VM, Vialetto E, Mougiakos I, Wandera KG, Domgaard H, Weber J, Gaudin T, Metcalf J, Gray BN, Begemann MB, Jackson RN, Beisel CL. Dmytrenko O, et al. Among authors: vialetto e. Nature. 2023 Jan;613(7944):588-594. doi: 10.1038/s41586-022-05559-3. Epub 2023 Jan 4. Nature. 2023. PMID: 36599979 Free PMC article.
Three-Dimensional Light Sheet Fluorescence Microscopy of Lungs To Dissect Local Host Immune-Aspergillus fumigatus Interactions.
Amich J, Mokhtari Z, Strobel M, Vialetto E, Sheta D, Yu Y, Hartweg J, Kalleda N, Jarick KJ, Brede C, Jordán-Garrote AL, Thusek S, Schmiedgen K, Arslan B, Pinnecker J, Thornton CR, Gunzer M, Krappmann S, Einsele H, Heinze KG, Beilhack A. Amich J, et al. Among authors: vialetto e. mBio. 2020 Feb 4;11(1):e02752-19. doi: 10.1128/mBio.02752-19. mBio. 2020. PMID: 32019790 Free PMC article.