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Blockade of Stat3 oncogene addiction induces cellular senescence and reveals a cell-nonautonomous activity suitable for cancer immunotherapy.
De Martino M, Tkach M, Bruni S, Rocha D, Mercogliano MF, Cenciarini ME, Chervo MF, Proietti CJ, Dingli F, Loew D, Fernández EA, Elizalde PV, Piaggio E, Schillaci R. De Martino M, et al. Among authors: mercogliano mf. Oncoimmunology. 2020 Jan 29;9(1):1715767. doi: 10.1080/2162402X.2020.1715767. eCollection 2020. Oncoimmunology. 2020. PMID: 32064174 Free PMC article.
p42/p44 MAPK-mediated Stat3Ser727 phosphorylation is required for progestin-induced full activation of Stat3 and breast cancer growth.
Tkach M, Rosemblit C, Rivas MA, Proietti CJ, Díaz Flaqué MC, Mercogliano MF, Beguelin W, Maronna E, Guzmán P, Gercovich FG, Deza EG, Elizalde PV, Schillaci R. Tkach M, et al. Among authors: mercogliano mf. Endocr Relat Cancer. 2013 Mar 22;20(2):197-212. doi: 10.1530/ERC-12-0194. Print 2013 Apr. Endocr Relat Cancer. 2013. PMID: 23329648 Free article.
Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy.
Díaz Flaqué MC, Galigniana NM, Béguelin W, Vicario R, Proietti CJ, Russo R, Rivas MA, Tkach M, Guzmán P, Roa JC, Maronna E, Pineda V, Muñoz S, Mercogliano M, Charreau EH, Yankilevich P, Schillaci R, Elizalde PV. Díaz Flaqué MC, et al. Breast Cancer Res. 2013 Dec 17;15(6):R118. doi: 10.1186/bcr3587. Breast Cancer Res. 2013. Retraction in: Breast Cancer Res. 2023 Nov 2;25(1):133. doi: 10.1186/s13058-023-01735-z. PMID: 24345432 Free PMC article. Retracted.
Stat3 regulates ErbB-2 expression and co-opts ErbB-2 nuclear function to induce miR-21 expression, PDCD4 downregulation and breast cancer metastasis.
Venturutti L, Romero LV, Urtreger AJ, Chervo MF, Cordo Russo RI, Mercogliano MF, Inurrigarro G, Pereyra MG, Proietti CJ, Izzo F, Díaz Flaqué MC, Sundblad V, Roa JC, Guzmán P, Bal de Kier Joffé ED, Charreau EH, Schillaci R, Elizalde PV. Venturutti L, et al. Among authors: mercogliano mf. Oncogene. 2016 Apr 28;35(17):2208-22. doi: 10.1038/onc.2015.281. Epub 2015 Jul 27. Oncogene. 2016. PMID: 26212010
MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1.
Venturutti L, Cordo Russo RI, Rivas MA, Mercogliano MF, Izzo F, Oakley RH, Pereyra MG, De Martino M, Proietti CJ, Yankilevich P, Roa JC, Guzmán P, Cortese E, Allemand DH, Huang TH, Charreau EH, Cidlowski JA, Schillaci R, Elizalde PV. Venturutti L, et al. Among authors: mercogliano mf. Oncogene. 2016 Dec 1;35(48):6189-6202. doi: 10.1038/onc.2016.151. Epub 2016 May 9. Oncogene. 2016. PMID: 27157613 Free PMC article.
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