Weinstein H - Search Results

1

Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.

Tang B, Li X, Maretzky T, Perez-Aguilar JM, McIlwain D, Xie Y, Zheng Y, Mak TW, Weinstein H, Blobel CP. Tang B, et al. Among authors: weinstein h. FASEB J. 2020 Apr;34(4):4956-4969. doi: 10.1096/fj.201902649R. Epub 2020 Feb 26. FASEB J. 2020. PMID: 32103528 Free PMC article.

2

A functional selectivity mechanism at the serotonin-2A GPCR involves ligand-dependent conformations of intracellular loop 2.

Perez-Aguilar JM, Shan J, LeVine MV, Khelashvili G, Weinstein H. Perez-Aguilar JM, et al. Among authors: weinstein h. J Am Chem Soc. 2014 Nov 12;136(45):16044-54. doi: 10.1021/ja508394x. Epub 2014 Oct 31. J Am Chem Soc. 2014. PMID: 25314362 Free PMC article.

3

Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.

Li X, Maretzky T, Perez-Aguilar JM, Monette S, Weskamp G, Le Gall S, Beutler B, Weinstein H, Blobel CP. Li X, et al. Among authors: weinstein h. J Cell Sci. 2017 Mar 1;130(5):868-878. doi: 10.1242/jcs.196436. Epub 2017 Jan 19. J Cell Sci. 2017. PMID: 28104813 Free PMC article.

4

Single-molecule analysis of ligand efficacy in β₂AR-G-protein activation.

Gregorio GG, Masureel M, Hilger D, Terry DS, Juette M, Zhao H, Zhou Z, Perez-Aguilar JM, Hauge M, Mathiasen S, Javitch JA, Weinstein H, Kobilka BK, Blanchard SC. Gregorio GG, et al. Among authors: weinstein h. Nature. 2017 Jul 6;547(7661):68-73. doi: 10.1038/nature22354. Epub 2017 Jun 7. Nature. 2017. PMID: 28607487 Free PMC article.

5

PDZ binding to the BAR domain of PICK1 is elucidated by coarse-grained molecular dynamics.

He Y, Liwo A, Weinstein H, Scheraga HA. He Y, et al. Among authors: weinstein h. J Mol Biol. 2011 Jan 7;405(1):298-314. doi: 10.1016/j.jmb.2010.10.051. Epub 2010 Nov 2. J Mol Biol. 2011. PMID: 21050858 Free PMC article.

6

Polarity conserved positions in transmembrane domains of G-protein coupled receptors and bacteriorhodopsin.

Zhang D, Weinstein H. Zhang D, et al. Among authors: weinstein h. FEBS Lett. 1994 Jan 10;337(2):207-12. doi: 10.1016/0014-5793(94)80274-2. FEBS Lett. 1994. PMID: 8287978 Free article.

7

The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter.

Shan J, Javitch JA, Shi L, Weinstein H. Shan J, et al. Among authors: weinstein h. PLoS One. 2011 Jan 27;6(1):e16350. doi: 10.1371/journal.pone.0016350. PLoS One. 2011. PMID: 21298009 Free PMC article.

8

How the dynamic properties and functional mechanisms of GPCRs are modulated by their coupling to the membrane environment.

Mondal S, Khelashvili G, Johner N, Weinstein H. Mondal S, et al. Among authors: weinstein h. Adv Exp Med Biol. 2014;796:55-74. doi: 10.1007/978-94-007-7423-0_4. Adv Exp Med Biol. 2014. PMID: 24158801 Review.

9

On the structural and mechanistic basis of function, classification, and ligand design for 5-HT receptors.

Weinstein H, Osman R. Weinstein H, et al. Neuropsychopharmacology. 1990 Oct-Dec;3(5-6):397-409. Neuropsychopharmacology. 1990. PMID: 2078275 Review.

10

Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6.

Carter M, Chen X, Slowinska B, Minnerath S, Glickstein S, Shi L, Campagne F, Weinstein H, Ross ME. Carter M, et al. Among authors: weinstein h. Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12843-8. doi: 10.1073/pnas.0501963102. Epub 2005 Aug 26. Proc Natl Acad Sci U S A. 2005. PMID: 16126904 Free PMC article.

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