Levin S - Search Results

1

The luminescent HiBiT peptide enables selective quantitation of G protein-coupled receptor ligand engagement and internalization in living cells.

Boursier ME, Levin S, Zimmerman K, Machleidt T, Hurst R, Butler BL, Eggers CT, Kirkland TA, Wood KV, Friedman Ohana R. Boursier ME, et al. Among authors: levin s. J Biol Chem. 2020 Apr 10;295(15):5124-5135. doi: 10.1074/jbc.RA119.011952. Epub 2020 Feb 27. J Biol Chem. 2020. PMID: 32107310 Free PMC article.

2

Target engagement and drug residence time can be observed in living cells with BRET.

Robers MB, Dart ML, Woodroofe CC, Zimprich CA, Kirkland TA, Machleidt T, Kupcho KR, Levin S, Hartnett JR, Zimmerman K, Niles AL, Ohana RF, Daniels DL, Slater M, Wood MG, Cong M, Cheng YQ, Wood KV. Robers MB, et al. Among authors: levin s. Nat Commun. 2015 Dec 3;6:10091. doi: 10.1038/ncomms10091. Nat Commun. 2015. PMID: 26631872 Free PMC article.

3

Equilibrium and Kinetic Measurements of Ligand Binding to HiBiT-tagged GPCRs on the Surface of Living Cells.

Boursier ME, Levin S, Hurst R, Ohana RF. Boursier ME, et al. Among authors: levin s. Bio Protoc. 2020 Dec 20;10(24):e3861. doi: 10.21769/BioProtoc.3861. eCollection 2020 Dec 20. Bio Protoc. 2020. PMID: 33659503 Free PMC article.

4

An Integrated Approach toward NanoBRET Tracers for Analysis of GPCR Ligand Engagement.

Killoran MP, Levin S, Boursier ME, Zimmerman K, Hurst R, Hall MP, Machleidt T, Kirkland TA, Friedman Ohana R. Killoran MP, et al. Among authors: levin s. Molecules. 2021 May 12;26(10):2857. doi: 10.3390/molecules26102857. Molecules. 2021. PMID: 34065854 Free PMC article.

5

Deciphering the Cellular Targets of Bioactive Compounds Using a Chloroalkane Capture Tag.

Ohana RF, Kirkland TA, Woodroofe CC, Levin S, Uyeda HT, Otto P, Hurst R, Robers MB, Zimmerman K, Encell LP, Wood KV. Ohana RF, et al. Among authors: levin s. ACS Chem Biol. 2015 Oct 16;10(10):2316-24. doi: 10.1021/acschembio.5b00351. Epub 2015 Aug 6. ACS Chem Biol. 2015. PMID: 26162280 Free article.

6

Improved Deconvolution of Protein Targets for Bioactive Compounds Using a Palladium Cleavable Chloroalkane Capture Tag.

Friedman Ohana R, Levin S, Wood MG, Zimmerman K, Dart ML, Schwinn MK, Kirkland TA, Hurst R, Uyeda HT, Encell LP, Wood KV. Friedman Ohana R, et al. Among authors: levin s. ACS Chem Biol. 2016 Sep 16;11(9):2608-17. doi: 10.1021/acschembio.6b00408. Epub 2016 Aug 3. ACS Chem Biol. 2016. PMID: 27414062 Free article.

7

Utilizing a Simple Method for Stoichiometric Protein Labeling to Quantify Antibody Blockade.

Friedman Ohana R, Hurst R, Rosenblatt M, Levin S, Machleidt T, Kirkland TA, Encell LP, Robers MB, Wood KV. Friedman Ohana R, et al. Among authors: levin s. Sci Rep. 2019 May 7;9(1):7046. doi: 10.1038/s41598-019-43469-z. Sci Rep. 2019. PMID: 31065015 Free PMC article.

8

Streamlined Target Deconvolution Approach Utilizing a Single Photoreactive Chloroalkane Capture Tag.

Friedman Ohana R, Levin S, Hurst R, Rosenblatt MM, Zimmerman K, Machleidt T, Wood KV, Kirkland TA. Friedman Ohana R, et al. Among authors: levin s. ACS Chem Biol. 2021 Feb 19;16(2):404-413. doi: 10.1021/acschembio.0c00987. Epub 2021 Feb 5. ACS Chem Biol. 2021. PMID: 33543920

9

Luminogenic HiBiT Peptide-Based NanoBRET Ligand Binding Assays for Melatonin Receptors.

Gbahou F, Levin S, Tikhonova IG, Somalo Barranco G, Izabelle C, Ohana RF, Jockers R. Gbahou F, et al. Among authors: levin s. ACS Pharmacol Transl Sci. 2022 Jul 18;5(8):668-678. doi: 10.1021/acsptsci.2c00096. eCollection 2022 Aug 12. ACS Pharmacol Transl Sci. 2022. PMID: 35983281 Free PMC article.

10

Scalable Regioselective Synthesis of Rhodamine Dyes.

Dwight SJ, Levin S. Dwight SJ, et al. Among authors: levin s. Org Lett. 2016 Oct 21;18(20):5316-5319. doi: 10.1021/acs.orglett.6b02635. Epub 2016 Oct 5. Org Lett. 2016. PMID: 27704864

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