Tang X - Search Results

1

Vascular endothelium-targeted Sirt7 gene therapy rejuvenates blood vessels and extends life span in a Hutchinson-Gilford progeria model.

Sun S, Qin W, Tang X, Meng Y, Hu W, Zhang S, Qian M, Liu Z, Cao X, Pang Q, Zhao B, Wang Z, Zhou Z, Liu B. Sun S, et al. Among authors: tang x. Sci Adv. 2020 Feb 19;6(8):eaay5556. doi: 10.1126/sciadv.aay5556. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128409 Free PMC article.

2

SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis.

Tang X, Shi L, Xie N, Liu Z, Qian M, Meng F, Xu Q, Zhou M, Cao X, Zhu WG, Liu B. Tang X, et al. Nat Commun. 2017 Aug 22;8(1):318. doi: 10.1038/s41467-017-00396-9. Nat Commun. 2017. PMID: 28827661 Free PMC article.

3

Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria.

Qian M, Liu Z, Peng L, Tang X, Meng F, Ao Y, Zhou M, Wang M, Cao X, Qin B, Wang Z, Zhou Z, Wang G, Gao Z, Xu J, Liu B. Qian M, et al. Among authors: tang x. Elife. 2018 May 2;7:e34836. doi: 10.7554/eLife.34836. Elife. 2018. PMID: 29717979 Free PMC article.

4

A SIRT1-centered circuitry regulates breast cancer stemness and metastasis.

Shi L, Tang X, Qian M, Liu Z, Meng F, Fu L, Wang Z, Zhu WG, Huang JD, Zhou Z, Liu B. Shi L, et al. Among authors: tang x. Oncogene. 2018 Dec;37(49):6299-6315. doi: 10.1038/s41388-018-0370-5. Epub 2018 Jul 23. Oncogene. 2018. PMID: 30038266 Free PMC article.

5

HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration.

Tang X, Li G, Su F, Cai Y, Shi L, Meng Y, Liu Z, Sun J, Wang M, Qian M, Wang Z, Xu X, Cheng YX, Zhu WG, Liu B. Tang X, et al. Nucleic Acids Res. 2020 Apr 6;48(6):2912-2923. doi: 10.1093/nar/gkaa039. Nucleic Acids Res. 2020. PMID: 31970414 Free PMC article.

6

Deacetylase-independent function of SIRT6 couples GATA4 transcription factor and epigenetic activation against cardiomyocyte apoptosis.

Peng L, Qian M, Liu Z, Tang X, Sun J, Jiang Y, Sun S, Cao X, Pang Q, Liu B. Peng L, et al. Among authors: tang x. Nucleic Acids Res. 2020 May 21;48(9):4992-5005. doi: 10.1093/nar/gkaa214. Nucleic Acids Res. 2020. PMID: 32239217 Free PMC article.

7

PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson-Gilford progeria syndrome.

Wang M, Wang L, Qian M, Tang X, Liu Z, Lai Y, Ao Y, Huang Y, Meng Y, Shi L, Peng L, Cao X, Wang Z, Qin B, Liu B. Wang M, et al. Among authors: tang x. Aging Cell. 2020 Jun;19(6):e13147. doi: 10.1111/acel.13147. Epub 2020 Apr 29. Aging Cell. 2020. PMID: 32351002 Free PMC article.

8

Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice.

Meng F, Qian M, Peng B, Peng L, Wang X, Zheng K, Liu Z, Tang X, Zhang S, Sun S, Cao X, Pang Q, Zhao B, Ma W, Songyang Z, Xu B, Zhu WG, Xu X, Liu B. Meng F, et al. Among authors: tang x. Elife. 2020 Jun 15;9:e55828. doi: 10.7554/eLife.55828. Elife. 2020. PMID: 32538779 Free PMC article.

9

SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis.

Liu Z, Qian M, Tang X, Hu W, Sun S, Li G, Zhang S, Meng F, Cao X, Sun J, Xu C, Tan B, Pang Q, Zhao B, Wang Z, Guan Y, Ruan X, Liu B. Liu Z, et al. Among authors: tang x. Nat Metab. 2019 Nov;1(11):1141-1156. doi: 10.1038/s42255-019-0136-6. Epub 2019 Nov 15. Nat Metab. 2019. PMID: 32694864

10

SIRT7 activates quiescent hair follicle stem cells to ensure hair growth in mice.

Li G, Tang X, Zhang S, Jin M, Wang M, Deng Z, Liu Z, Qian M, Shi W, Wang Z, Xie H, Li J, Liu B. Li G, et al. Among authors: tang x. EMBO J. 2020 Sep 15;39(18):e104365. doi: 10.15252/embj.2019104365. Epub 2020 Jul 21. EMBO J. 2020. PMID: 32696520 Free PMC article.

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