Bonini NM - Search Results

1

TDP-43, a protein central to amyotrophic lateral sclerosis, is destabilized by tankyrase-1 and -2.

McGurk L, Rifai OM, Bonini NM. McGurk L, et al. Among authors: bonini nm. J Cell Sci. 2020 Jun 23;133(12):jcs245811. doi: 10.1242/jcs.245811. J Cell Sci. 2020. PMID: 32409565 Free PMC article.

2

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila.

Warrick JM, Paulson HL, Gray-Board GL, Bui QT, Fischbeck KH, Pittman RN, Bonini NM. Warrick JM, et al. Among authors: bonini nm. Cell. 1998 Jun 12;93(6):939-49. doi: 10.1016/s0092-8674(00)81200-3. Cell. 1998. PMID: 9635424 Free article.

3

A drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1.

Watson MR, Lagow RD, Xu K, Zhang B, Bonini NM. Watson MR, et al. Among authors: bonini nm. J Biol Chem. 2008 Sep 5;283(36):24972-81. doi: 10.1074/jbc.M804817200. Epub 2008 Jul 2. J Biol Chem. 2008. PMID: 18596033 Free PMC article.

4

Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis.

Lee T, Li YR, Chesi A, Hart MP, Ramos D, Jethava N, Hosangadi D, Epstein J, Hodges B, Bonini NM, Gitler AD. Lee T, et al. Among authors: bonini nm. Neurology. 2011 Jun 14;76(24):2062-5. doi: 10.1212/WNL.0b013e31821f4447. Epub 2011 May 11. Neurology. 2011. PMID: 21562248 Free PMC article.

5

Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila.

McGurk L, Bonini NM. McGurk L, et al. Among authors: bonini nm. Hum Mol Genet. 2012 Jan 1;21(1):76-84. doi: 10.1093/hmg/ddr439. Epub 2011 Sep 23. Hum Mol Genet. 2012. PMID: 21949352 Free PMC article.

6

Cell biology. Yeast informs Alzheimer's disease.

McGurk L, Bonini NM. McGurk L, et al. Among authors: bonini nm. Science. 2011 Dec 2;334(6060):1212-3. doi: 10.1126/science.1216073. Science. 2011. PMID: 22144604 No abstract available.

7

Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models.

Kim HJ, Raphael AR, LaDow ES, McGurk L, Weber RA, Trojanowski JQ, Lee VM, Finkbeiner S, Gitler AD, Bonini NM. Kim HJ, et al. Among authors: bonini nm. Nat Genet. 2014 Feb;46(2):152-60. doi: 10.1038/ng.2853. Epub 2013 Dec 15. Nat Genet. 2014. PMID: 24336168 Free PMC article.

8

Poly-A binding protein-1 localization to a subset of TDP-43 inclusions in amyotrophic lateral sclerosis occurs more frequently in patients harboring an expansion in C9orf72.

McGurk L, Lee VM, Trojanowksi JQ, Van Deerlin VM, Lee EB, Bonini NM. McGurk L, et al. Among authors: bonini nm. J Neuropathol Exp Neurol. 2014 Sep;73(9):837-45. doi: 10.1097/NEN.0000000000000102. J Neuropathol Exp Neurol. 2014. PMID: 25111021 Free PMC article.

9

Drosophila as an In Vivo Model for Human Neurodegenerative Disease.

McGurk L, Berson A, Bonini NM. McGurk L, et al. Among authors: bonini nm. Genetics. 2015 Oct;201(2):377-402. doi: 10.1534/genetics.115.179457. Genetics. 2015. PMID: 26447127 Free PMC article. Review.

10

TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling.

Berson A, Sartoris A, Nativio R, Van Deerlin V, Toledo JB, Porta S, Liu S, Chung CY, Garcia BA, Lee VM, Trojanowski JQ, Johnson FB, Berger SL, Bonini NM. Berson A, et al. Among authors: bonini nm. Curr Biol. 2017 Dec 4;27(23):3579-3590.e6. doi: 10.1016/j.cub.2017.10.024. Epub 2017 Nov 16. Curr Biol. 2017. PMID: 29153328 Free PMC article.

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