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Chromatin as a key consumer in the metabolite economy.
Diehl KL, Muir TW. Diehl KL, et al. Nat Chem Biol. 2020 Jun;16(6):620-629. doi: 10.1038/s41589-020-0517-x. Epub 2020 May 22. Nat Chem Biol. 2020. PMID: 32444835 Free PMC article. Review.
Acetylation blocks DNA damage-induced chromatin ADP-ribosylation.
Liszczak G, Diehl KL, Dann GP, Muir TW. Liszczak G, et al. Among authors: diehl kl. Nat Chem Biol. 2018 Sep;14(9):837-840. doi: 10.1038/s41589-018-0097-1. Epub 2018 Jul 16. Nat Chem Biol. 2018. PMID: 30013063 Free PMC article.
PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor.
Diehl KL, Ge EJ, Weinberg DN, Jani KS, Allis CD, Muir TW. Diehl KL, et al. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22152-22157. doi: 10.1073/pnas.1911775116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611394 Free PMC article.
Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes.
Zhou X, Feliciano P, Shu C, Wang T, Astrovskaya I, Hall JB, Obiajulu JU, Wright JR, Murali SC, Xu SX, Brueggeman L, Thomas TR, Marchenko O, Fleisch C, Barns SD, Snyder LG, Han B, Chang TS, Turner TN, Harvey WT, Nishida A, O'Roak BJ, Geschwind DH; SPARK Consortium; Michaelson JJ, Volfovsky N, Eichler EE, Shen Y, Chung WK. Zhou X, et al. Nat Genet. 2022 Sep;54(9):1305-1319. doi: 10.1038/s41588-022-01148-2. Epub 2022 Aug 18. Nat Genet. 2022. PMID: 35982159 Free PMC article.
34 results