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N-alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity.
Keenan B, Finol-Urdaneta RK, Hope A, Bremner JB, Kavallaris M, Lucena-Agell D, Oliva MÁ, Díaz JF, Vine KL. Keenan B, et al. Among authors: kavallaris m. Cancer Cell Int. 2020 May 15;20:170. doi: 10.1186/s12935-020-01251-6. eCollection 2020. Cancer Cell Int. 2020. PMID: 32467666 Free PMC article.
Involvement of MDR1 P-glycoprotein in multifactorial resistance to methotrexate.
Norris MD, De Graaf D, Haber M, Kavallaris M, Madafiglio J, Gilbert J, Kwan E, Stewart BW, Mechetner EB, Gudkov AV, Roninson IB. Norris MD, et al. Among authors: kavallaris m. Int J Cancer. 1996 Mar 1;65(5):613-9. doi: 10.1002/(SICI)1097-0215(19960301)65:5<613::AID-IJC10>3.0.CO;2-8. Int J Cancer. 1996. PMID: 8598312
Cytoskeleton and paclitaxel sensitivity in breast cancer: the role of beta-tubulins.
Tommasi S, Mangia A, Lacalamita R, Bellizzi A, Fedele V, Chiriatti A, Thomssen C, Kendzierski N, Latorre A, Lorusso V, Schittulli F, Zito F, Kavallaris M, Paradiso A. Tommasi S, et al. Among authors: kavallaris m. Int J Cancer. 2007 May 15;120(10):2078-85. doi: 10.1002/ijc.22557. Int J Cancer. 2007. PMID: 17285590
186 results