Tian Y - Search Results

1

Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for Organic Anion-Transporting Polypeptide Inhibition.

Gu X, Wang L, Gan J, Fancher RM, Tian Y, Hong Y, Lai Y, Sinz M, Shen H. Gu X, et al. Among authors: tian y. Drug Metab Dispos. 2020 Aug;48(8):724-734. doi: 10.1124/dmd.120.090670. Epub 2020 Jun 1. Drug Metab Dispos. 2020. PMID: 32482623

2

Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human liver drug transporters.

Han YH, Busler D, Hong Y, Tian Y, Chen C, Rodrigues AD. Han YH, et al. Among authors: tian y. Drug Metab Dispos. 2010 Jul;38(7):1072-82. doi: 10.1124/dmd.109.031518. Epub 2010 Apr 1. Drug Metab Dispos. 2010. PMID: 20360302

3

Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human kidney drug transporters.

Han YH, Busler D, Hong Y, Tian Y, Chen C, Rodrigues AD. Han YH, et al. Among authors: tian y. Drug Metab Dispos. 2010 Jul;38(7):1064-71. doi: 10.1124/dmd.109.031526. Epub 2010 Apr 1. Drug Metab Dispos. 2010. PMID: 20360303

4

CYP3A4-mediated ester cleavage as the major metabolic pathway of the oral taxane 3'-tert-butyl-3'-N-tert-butyloxycarbonyl-4-deacetyl-3'-dephenyl-3'-N-debenzoyl-4-O-methoxycarbonyl-paclitaxel (BMS-275183).

Zhang D, Ly VT, Lago M, Tian Y, Gan J, Humphreys WG, Cömezoglu SN. Zhang D, et al. Among authors: tian y. Drug Metab Dispos. 2009 Apr;37(4):710-8. doi: 10.1124/dmd.108.024398. Epub 2009 Jan 21. Drug Metab Dispos. 2009. PMID: 19158314

5

Tissue distribution and tumor uptake of folate receptor-targeted epothilone folate conjugate, BMS-753493, in CD2F1 mice after systemic administration.

Shen H, Wang L, Chen W, Menard K, Hong Y, Tian Y, Bonacorsi SJ, Humphreys WG, Lee FY, Gan J. Shen H, et al. Among authors: tian y. Acta Pharm Sin B. 2016 Sep;6(5):460-467. doi: 10.1016/j.apsb.2016.07.009. Epub 2016 Aug 11. Acta Pharm Sin B. 2016. PMID: 27709015 Free PMC article.

6

Repaglinide-gemfibrozil drug interaction: inhibition of repaglinide glucuronidation as a potential additional contributing mechanism.

Gan J, Chen W, Shen H, Gao L, Hong Y, Tian Y, Li W, Zhang Y, Tang Y, Zhang H, Humphreys WG, Rodrigues AD. Gan J, et al. Among authors: tian y. Br J Clin Pharmacol. 2010 Dec;70(6):870-80. doi: 10.1111/j.1365-2125.2010.03772.x. Br J Clin Pharmacol. 2010. PMID: 21175442 Free PMC article.

7

Preclinical metabolism and disposition of an orally bioavailable macrocyclic FXIa inhibitor.

Chacko SA, Yang W, Wang Y, Tian Y, Hong Y, Wallace M, Wang B, Ewing WR, Luettgen JM, Shu YZ, Christopher LJ. Chacko SA, et al. Among authors: tian y. Xenobiotica. 2021 Aug;51(8):933-948. doi: 10.1080/00498254.2021.1943565. Epub 2021 Jul 5. Xenobiotica. 2021. PMID: 34151691

8

Synthesis of tritium labeled 30-KDa PEG and conjugation to form [³ H]Pegbelfermin.

Easter JA, Tian Y, Burrell RC, Hong Y, Bonacorsi SJ Jr. Easter JA, et al. Among authors: tian y. J Labelled Comp Radiopharm. 2021 Oct;64(12):477-481. doi: 10.1002/jlcr.3940. Epub 2021 Aug 23. J Labelled Comp Radiopharm. 2021. PMID: 34386991

9

Synthesis of [3α-(3) H] 17α-hydroxy pregnenolone and [3α-(3) H] pregnenolone.

Tian Y, Hong Y, Bonacorsi SJ, Balog A, Gong S. Tian Y, et al. J Labelled Comp Radiopharm. 2014 Jan;57(1):1-11. doi: 10.1002/jlcr.3114. Epub 2013 Oct 24. J Labelled Comp Radiopharm. 2014. PMID: 24448740

10

Inhibition of in vivo [(3)H]MK-801 binding by NMDA receptor open channel blockers and GluN2B antagonists in rats and mice.

Fernandes A, Wojcik T, Baireddy P, Pieschl R, Newton A, Tian Y, Hong Y, Bristow L, Li YW. Fernandes A, et al. Among authors: tian y. Eur J Pharmacol. 2015 Nov 5;766:1-8. doi: 10.1016/j.ejphar.2015.08.044. Epub 2015 Aug 29. Eur J Pharmacol. 2015. PMID: 26325093

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