Chen L - Search Results

1

p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs.

Choi HY, Siddique HR, Zheng M, Kou Y, Yeh DW, Machida T, Chen CL, Uthaya Kumar DB, Punj V, Winer P, Pita A, Sher L, Tahara SM, Ray RB, Liang C, Chen L, Tsukamoto H, Machida K. Choi HY, et al. Among authors: chen l, chen cl. Nat Commun. 2020 Jun 17;11(1):3084. doi: 10.1038/s41467-020-16616-8. Nat Commun. 2020. PMID: 32555153 Free PMC article.

2

Mining 3D genome structure populations identifies major factors governing the stability of regulatory communities.

Dai C, Li W, Tjong H, Hao S, Zhou Y, Li Q, Chen L, Zhu B, Alber F, Jasmine Zhou X. Dai C, et al. Among authors: chen l. Nat Commun. 2016 May 31;7:11549. doi: 10.1038/ncomms11549. Nat Commun. 2016. PMID: 27240697 Free PMC article.

3

Nicotinic acetylcholine receptor agonist attenuates ILC2-dependent airway hyperreactivity.

Galle-Treger L, Suzuki Y, Patel N, Sankaranarayanan I, Aron JL, Maazi H, Chen L, Akbari O. Galle-Treger L, et al. Among authors: chen l. Nat Commun. 2016 Oct 18;7:13202. doi: 10.1038/ncomms13202. Nat Commun. 2016. PMID: 27752043 Free PMC article.

4

The Cancer Mutation D83V Induces an α-Helix to β-Strand Conformation Switch in MEF2B.

Lei X, Kou Y, Fu Y, Rajashekar N, Shi H, Wu F, Xu J, Luo Y, Chen L. Lei X, et al. Among authors: chen l. J Mol Biol. 2018 Apr 13;430(8):1157-1172. doi: 10.1016/j.jmb.2018.02.012. Epub 2018 Feb 22. J Mol Biol. 2018. PMID: 29477338

5

Crystal Structure of Apo MEF2B Reveals New Insights in DNA Binding and Cofactor Interaction.

Lei X, Shi H, Kou Y, Rajashekar N, Wu F, Sen C, Xu J, Chen L. Lei X, et al. Among authors: chen l. Biochemistry. 2018 Jul 17;57(28):4047-4051. doi: 10.1021/acs.biochem.8b00439. Epub 2018 Jul 5. Biochemistry. 2018. PMID: 29944822

6

Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis.

Wei H, Qu L, Dai S, Li Y, Wang H, Feng Y, Chen X, Jiang L, Guo M, Li J, Chen Z, Chen L, Zhang Y, Chen Y. Wei H, et al. Among authors: chen z, chen l, chen x, chen y. Nat Commun. 2021 Apr 16;12(1):2280. doi: 10.1038/s41467-021-22655-6. Nat Commun. 2021. PMID: 33863900 Free PMC article.

7

Hypertonic Dextrose Stimulates Chondrogenic Cells to Deposit Collagen and Proliferate.

Johnston E, Kou Y, Junge J, Chen L, Kochan A, Johnston M, Rabago D. Johnston E, et al. Among authors: chen l. Cartilage. 2021 Dec;13(2_suppl):213S-224S. doi: 10.1177/19476035211014572. Epub 2021 Jun 10. Cartilage. 2021. PMID: 34109827 Free PMC article.

8

Novel Few-Shot Learning Neural Network for Predicting Carbohydrate-Active Enzyme Affinity Toward Fructo-Oligosaccharides.

Liu S, Kou Y, Chen L. Liu S, et al. Among authors: chen l. J Comput Biol. 2021 Dec;28(12):1208-1218. doi: 10.1089/cmb.2021.0091. J Comput Biol. 2021. PMID: 34898254

9

NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells.

Choi HY, Zhu Y, Zhao X, Mehta S, Hernandez JC, Lee JJ, Kou Y, Machida R, Giacca M, Del Sal G, Ray R, Eoh H, Tahara SM, Chen L, Tsukamoto H, Machida K. Choi HY, et al. Among authors: chen l. Exp Mol Med. 2024 Feb;56(2):461-477. doi: 10.1038/s12276-024-01174-6. Epub 2024 Feb 27. Exp Mol Med. 2024. PMID: 38409448 Free PMC article.

10

Transcript errors generate amyloid-like proteins in huwman cells.

Chung CS, Kou Y, Shemtov SJ, Verheijen BM, Flores I, Love K, Del Dosso A, Thorwald MA, Liu Y, Hicks D, Sun Y, Toney RG, Carrillo L, Nguyen MM, Biao H, Jin Y, Jauregui AM, Quiroz JD, Head E, Moore DL, Simpson S, Thomas KW, Coba MP, Li Z, Benayoun BA, Rosenthal JJC, Kennedy SR, Quadrato G, Gout JF, Chen L, Vermulst M. Chung CS, et al. Among authors: chen l. Nat Commun. 2024 Oct 7;15(1):8676. doi: 10.1038/s41467-024-52886-2. Nat Commun. 2024. PMID: 39375347 Free PMC article.

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